BODY COMP/CORONARY RISK FACTOR INTERACTIONS IN REHAB OF OLDER CORONARY PTS.

老年冠心病患者康复中身体成分/冠心病风险因素的相互作用。

• 批准号: 6247010
• 负责人: PHILIP A. ADES
• 金额: $ 2.44万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-23 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6247010
• 关键词: aerobic exercise; age difference; blood lipid; blood pressure; body composition; clinical research; coronary disorder; disease /disorder proneness /risk; human old age (65+); human subject; insulin; physical fitness; rehabilitation

In this study, 105 coronary patients have undergone evaluations which include exercise stress testing, 24 hour dietary recall, fasting lipid profiles, insulin and glucose levels and dual x-ray absorptiometry. Of these, 71 have returned for repeat testing after 3 months of cardiac rehabilitation exercise training. The primary study hypothesis is that training-induced changes in body composition and body fat distribution will predict favorable changes in several cardiac risk factors including serum triglycerides, HDL-cholesterol, glucose and insulin levels. Our initial analysis focused on body composition and body fat distribution in older female coronary patients. We found that waist to hip ratio (WHR) was significantly correlated with serum triglycerides (r=0.65, P=0.002), HDL-chol (r=0.46, P=0.05) and fasting insulin levels (r=0.76, P<0.001). Peak oxygen consumption was the best predictor of LDL-chol (r=0.73, P<0.01). We wll soon be supplementing this analysis wth data on response of these variables to exercise conditioning. We expect that these data will focus attention of the importance of WHR as an outcome variable in the rehabilitation of coronary patients.

在本研究中，105名冠状动脉患者接受了评估