CEREBRAL PROCESSING OF MENTAL ROTATION

心理旋转的大脑处理

• 批准号: 6282822
• 负责人: APOSTOLOS GEORGOPOULOS
• 金额: $ 5.48万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-15 至 1999-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6282822
• 关键词: biomedical resource; cognition; female; human subject; magnetic resonance imaging; male; nervous system

This collaborative effort is supported by an NIH grant for human fMRI studies (R01 NS 32919, 7/15/94- 4/30/97). The overall goal of this project is to determine the spatio-temporal patterns of functional activation of cortical areas during performance of specific perceptual-motor cognitive tasks, as revealed by high field functional magnetic resonance imaging in human brain. SPECIFIC AIMS are: 1. To determine the spatio-temporal patterns of functional activation of cortical areas during visual and motor mental rotation in the human brain using fMRI and correlate activation in these areas with behavioral data obtained simultaneously with the MR images. Specifically, this project is aimed (a) to identify the areas involved during mental rotation of visual images and during generation of movements at an angle from a stimulus direction, and (b) to test the hypotheses that these cognitive processes (i) involve the sequential activation of specific cortical areas, and (ii) rely on the activation of certain common cortical areas. 2. To determine the spatio-temporal patterns of functional activation of cortical areas during visual and motor memory scanning. This project is aimed (a) to identify the areas involved during memory scanning of visual images and during generation of movements based on memory scanning of a previous sequence, and (b) to test the hypotheses that these cognitive processes (i) involve the sequential activation of specific cortical areas, and (ii) rely on the activation of common cortical areas. 3. To compare the spatio-temporal patterns of functional activation of cortical areas obtained during mental rotation and memory scanning. This comparison will serve to differentiate the cortical substrates involved in these two different kinds of cognitive processes . In the last year, significant progress has been made towards aims 1 and 2 and partially into specific aim 3. Currently data are being collected on specific aim 3. Two papers are in press. Another one has been submitted.

这项合作努力得到了NIH资助的人类 fMRI研究（R 01 NS 32919，7/15/94- 4/30/97）。 的总目标 这个项目是为了确定 在执行特定任务期间， 知觉运动认知任务，如高场功能所揭示的 核磁共振成像技术。 具体目标是：1。 到 确定功能激活的时空模式， 人类视觉和运动心理旋转过程中的皮质区 大脑功能磁共振成像，并将这些区域的激活与 与MR图像同时获得的行为数据。 具体而言，该项目旨在：（a）确定所涉领域 在视觉图像的心理旋转期间以及在 以与刺激方向成一定角度的运动，以及（B）为了测试所述运动， 假设这些认知过程（i）涉及顺序 激活特定的皮层区域，以及（ii）依赖于激活 某些常见的皮层区域。 2. 确定 皮层区功能激活的时空模式 进行视觉和运动记忆扫描 该项目的目标是：（a） 识别视觉图像记忆扫描过程中涉及的区域 并且在基于对运动的存储器扫描生成运动期间， （B）检验这些认知的假设 过程（i）涉及特定皮层的顺序激活 区域，和（ii）依赖于共同的皮层区域的激活。 3. 为了比较功能激活的时空模式， 大脑皮层区域在心理旋转和记忆扫描过程中获得。 这种比较将有助于区分皮质基底 参与了这两种不同的认知过程。 在 去年，在实现目标1和2方面取得了重大进展， 3、具体目标。 目前正在收集数据， 具体目标3. 有两份报纸正在印刷中. 另一个是 提交的。