CEREBRAL PROCESSING OF MENTAL ROTATION

这一合作努力得到了美国国立卫生研究院对人类的资助 功能磁共振研究(R01 NS 32919，7/15/94-4/30/97)。的总目标是 这个项目是为了确定宇宙的时空模式 特异功能运动中皮质区域的功能激活 高场函数揭示的知觉-运动认知任务 人脑的磁共振成像。具体目标是：1. 确定脑功能激活的时空模式 人类视觉和运动性心理旋转过程中的皮质区域 脑功能磁共振成像和这些区域的激活与 与磁共振图像同时获得的行为数据。 具体地说，该项目的目的是(A)确定所涉及的领域 在视觉图像的心理旋转期间和在生成 与刺激方向成一定角度的运动，以及(B)测试 假设这些认知过程(I)涉及序列 激活特定皮质区域，以及(Ii)依赖于激活 某些共同的皮质区域。2.确定 大脑皮层功能区激活的时空模式 在视觉和运动记忆扫描期间。这个项目的目的是(A) 识别视觉图像的记忆扫描过程中涉及的区域 并且在基于存储器扫描的移动的生成期间 之前的序列，以及(B)测试这些认知的假设 过程(I)涉及特定皮质的顺序激活 (2)依赖于共同皮质区域的激活。3. 比较脑功能激活的时空模式 在心理旋转和记忆扫描过程中获得的皮质区域。 这种比较将有助于区分皮质底物。 参与了这两种不同的认知过程。在 去年，在实现目标1和目标2以及 部分用于具体目标3.目前正在收集关于 具体目标3.有两篇论文正在印刷中。另一次是 已提交。

This collaborative effort is supported by an NIH grant for human fMRI studies (R01 NS 32919, 7/15/94- 4/30/97). The overall goal of this project is to determine the spatio-temporal patterns of functional activation of cortical areas during performance of specific perceptual-motor cognitive tasks, as revealed by high field functional magnetic resonance imaging in human brain. SPECIFIC AIMS are: 1. To determine the spatio-temporal patterns of functional activation of cortical areas during visual and motor mental rotation in the human brain using fMRI and correlate activation in these areas with behavioral data obtained simultaneously with the MR images. Specifically, this project is aimed (a) to identify the areas involved during mental rotation of visual images and during generation of movements at an angle from a stimulus direction, and (b) to test the hypotheses that these cognitive processes (i) involve the sequential activation of specific cortical areas, and (ii) rely on the activation of certain common cortical areas. 2. To determine the spatio-temporal patterns of functional activation of cortical areas during visual and motor memory scanning. This project is aimed (a) to identify the areas involved during memory scanning of visual images and during generation of movements based on memory scanning of a previous sequence, and (b) to test the hypotheses that these cognitive processes (i) involve the sequential activation of specific cortical areas, and (ii) rely on the activation of common cortical areas. 3. To compare the spatio-temporal patterns of functional activation of cortical areas obtained during mental rotation and memory scanning. This comparison will serve to differentiate the cortical substrates involved in these two different kinds of cognitive processes . In the last year, significant progress has been made towards aims 1 and 2 and partially into specific aim 3. Currently data are being collected on specific aim 3. Two papers are in press. Another one has been submitted.