HIGH INTENSITY X RAY SOURCE FOR MEDICAL IMAGING

用于医学成像的高强度 X 射线源

• 批准号: 2718042
• 负责人: Melvin Arthur Piestrup
• 金额: $ 46.45万
• 依托单位: ADELPHI TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-04-08 至 2000-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2718042
• 关键词: X ray; bioengineering /biomedical engineering; biomedical equipment development; clinical biomedical equipment; digital imaging; electron radiation; image enhancement; imaging /visualization /scanning; mammography; particle accelerators; particle beam; phantom model; radiography

The objective of the proposed research is to construct a prototype narrow-bandwidth x-ray source for medical imaging using a compact betatron and a parametric x-radiator (PXR). The device will resemble a "table-top synchrotron" in that it uses a recirculated electron beam to produce intense collimated quasimonochromatic x rays. Such a source will provide higher quality radiograph images while lowering the dose to the patient. The research will proceed by completing the design of the betatron/PXR source using available betatron technology. The compact source will then be assembled and quasimonochromatic x rays generated. Methods to further increase the brightness of the source will be explored experimentally. Finally, images of inanimate phantoms will be used to quantify the imaging system's characteristics. The PXR images will also be compared with those taken from a conventional mammography unit. The potential for successful development of the prototype imaging system is very high because our phase I research has experimentally demonstrated both electron recycling and narrow-bandwidth PXR generation. These results indicate that a high quality mammogram can be generated in less than 3 seconds. PROPOSED COMMERCIAL APPLICATION: A compact, inexpensive x-ray source with characteristics similar to the synchrotron has benefits of making high x-ray fluxes more accessible. The natural collimation of PXR permits reduced scattering while the narrow bandwidth and frequency selection optimizes contrast and reduces dose.

拟议研究的目的是构建原型 使用紧凑的窄带宽带X射线源用于医学成像 betatron和参数X-Radiator（PXR）。 该设备将类似 “桌面同步器”，因为它使用了循环电子束 产生强烈的准确的准杂色X射线。 这样的来源 将提供更高质量的X光片图像，同时降低剂量 给病人。 这项研究将通过完成设计 使用可用的Betatron技术的Betatron/PXR源。 这 然后，将组装紧凑源并进行准杂色X射线 生成。 进一步提高源亮度的方法 将通过实验探索。 最后，无生命的幻象图像 将用于量化成像系统的特性。 PXR 图像也将与传统的图像进行比较 乳房X线摄影单元。 成功开发原型成像系统的潜力 很高，因为我们的I阶段研究已在实验上进行 展示了电子回收和窄带宽度PXR 一代。 这些结果表明，高质量的乳房X线照片可以 在不到3秒钟内生成。 拟议的商业应用： 一个紧凑，廉价的X射线源，具有类似于 同步器具有使高X射线通量更容易访问的好处。 PXR的自然准则允许减少散射 狭窄的带宽和频率选择优化对比度和减少 剂量。