CHANNELING RADIATION FOR NON-INVASIVE ANGIOGRAPHY

用于非侵入性血管造影的引导辐射

• 批准号: 3508572
• 负责人: Melvin Arthur Piestrup
• 金额: $ 25万
• 依托单位: ADELPHI TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-09-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3508572
• 关键词: X ray; angiography; cardiovascular disorder diagnosis; clinical biomedical equipment; diagnosis design /evaluation; noninvasive diagnosis

The objective of this project is to develop a channeling x-ray source for non-invasive screening for coronary artery disease. Under the Phase I grant the investigators demonstrated the feasibility of using channeling radiation, produced by the passage of a moderate-energy electron beam through a crystal, for dual-energy, digital subtraction coronary angiography. To continue developing a channeling x-ray source, we have set four goals for our proposed Phase II research: 1_ Measure the channeling radiation energy spectrum at high peak currents; 2) Design, construct, and test a precision crystal rotator to maintain low average crystal temperature during the production of high intensity channeling radiation; 3) Develop a dual-energy source that can easily change the peak photon energy; 4) Measure x-ray images of inanimate phantoms to test the performance of the channeling radiation source; evaluate the influence of coronary artery iodine concentration and source brightness on image quality.

该项目的目标是开发一种沟道X射线源， 冠状动脉疾病的非侵入性筛查。第一期 格兰特研究人员证明了利用通道的可行性 由中等能量的电子束通过而产生的辐射 双能量数字减影冠状动脉 动脉造影 为了继续开发一个通道X射线源，我们设定了四个目标 对于我们提出的第二阶段研究：1_测量沟道辐射 高峰电流下的能谱; 2）设计、构造和测试 保持低平均晶体温度的精密晶体旋转器 在高强度沟道辐射的生产过程中; 3）开发 双能量源，可以很容易地改变峰值光子能量; 4） 测量无生命体的X射线图像，以测试 引导放射源;评价冠状动脉的影响 碘浓度和光源亮度对图像质量的影响。

项目成果

Noninvasive digital energy subtraction angiography with a channeling-radiation x-ray source.

使用通道辐射 X 射线源进行无创数字能量减影血管造影。

• DOI: 10.1118/1.597116
• 发表时间: 1993
• 期刊: Medical physics
• 影响因子: 3.8
• 作者: Gary,CK;Piestrup,MA;Boyers,DG;Pincus,CI;Pantell,RH;Rothbart,GB
• 通讯作者: Rothbart,GB