CHANNELING RADIATION FOR NON-INVASIVE ANGIOGRAPHY

该项目的目标是开发一种通道x射线源，用于 冠状动脉疾病的无创性筛查。在第一阶段下 格兰特向调查人员演示了使用通灵的可行性 由中能电子束通过而产生的辐射 通过一颗水晶，进行双能、数字减影冠状动脉 血管造影术。 为了继续开发通道x射线源，我们设定了四个目标 对于我们提议的第二阶段研究：1_测量沟道辐射 高峰值电流下的能谱；2)设计、建造和测试 保持低平均结晶温度的精密晶体旋转器 在高强度沟道辐射的生产中；3)开发 可轻松改变峰值光子能量的双能源；4) 测量无生命体模的x射线图像以测试 引导放射源；评价冠脉病变的影响 碘浓度和光源亮度对图像质量的影响。

The objective of this project is to develop a channeling x-ray source for non-invasive screening for coronary artery disease. Under the Phase I grant the investigators demonstrated the feasibility of using channeling radiation, produced by the passage of a moderate-energy electron beam through a crystal, for dual-energy, digital subtraction coronary angiography. To continue developing a channeling x-ray source, we have set four goals for our proposed Phase II research: 1_ Measure the channeling radiation energy spectrum at high peak currents; 2) Design, construct, and test a precision crystal rotator to maintain low average crystal temperature during the production of high intensity channeling radiation; 3) Develop a dual-energy source that can easily change the peak photon energy; 4) Measure x-ray images of inanimate phantoms to test the performance of the channeling radiation source; evaluate the influence of coronary artery iodine concentration and source brightness on image quality.