Quasi-monochromatic X-ray Source for Mammography

用于乳腺X线摄影的准单色X射线源

• 批准号: 6669658
• 负责人: Melvin Arthur Piestrup
• 金额: $ 38.35万
• 依托单位: ADELPHI TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6669658
• 关键词: X ray; beta radiation; bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; diagnosis design /evaluation; energy source; image enhancement; mammography; particle accelerators; particle beam; radiation dosage

Description (provided by applicant): The objective of the proposed research is to construct a prototype narrow-bandwidth x-ray source for mammography using a thin, efficient hybrid radiator driven by a relativistic electron beam of moderate energy and current. The high x-ray yield (photons/electron) of the source permits the use of modest electron-beam currents, preventing thermal damage to the radiator itself. The radiator is thin, permitting the electron beam to pass through it many times, thereby proportionally increasing the emitted x-ray flux. Since the source is inherently collimated and quasi-monochromatic, it will produce higher quality radiographic images while lowering the dose to the patient. Phase I experiments have demonstrated intense quasi-monochromatic x-rays in the range optimum for mammography (15 to 25 keV). Calculations of the x-ray yield and the average current passing through the radiator have demonstrated that there is adequate flux for imaging. The research will proceed by improving the design of the thin hybrid radiator and experimentally demonstrating its feasibility by producing images of inanimate phantoms. The potential for successful development of the prototype imaging system is very high because our Phase I research has already experimentally demonstrated, both electron recycling and narrow bandwidth, tunable x-ray generation. These results indicate that a high quality mammogram can be generated in less than 3 seconds.

描述(由申请人提供)：建议研究的目标是 为了构建用于乳房X光摄影的窄带x射线源原型， 由相对论电子束驱动的薄型高效混合辐射器 中等能量和电流。高X射线产额(光子/电子) 信号源允许使用适度的电子束电流，防止热 对散热器本身造成损坏。散热器很薄，允许电子 使光束多次穿过它，从而按比例增加 发射出的X射线通量。因为光源本身就是准直的， 准单色，它将产生更高质量的射线图像，而 降低给病人的剂量。第一阶段的实验表明， 适用于乳房X光摄影的最佳范围内的准单色X射线(15至25keV)。 X射线产额和流过的平均电流的计算 散热器已经证明，有足够的流量进行成像。这个 研究将通过改进薄型混合散热器的设计和 通过制作无生命的图像来实验证明其可行性 幻影。成功开发原型成像的潜力 系统非常高，因为我们的第一阶段研究已经在实验中 展示了电子循环和窄带宽可调x射线 一代。这些结果表明，高质量的乳房X光照片可以 在不到3秒的时间内生成。