CESIUM IODIDE CONVERTER FOR RADIATION THERAPY

用于放射治疗的碘化铯转换器

• 批准号: 6072457
• 负责人: GERALD ENTINE
• 金额: $ 10万
• 依托单位: RADIATION MONITORING DEVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-14 至 2000-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6072457
• 关键词: biomedical equipment development; cesium; image enhancement; radiation detector; radiation therapy; silicon

DESCRIPTION: The investigators propose to test the feasibility of developing a more efficient area detector for high energy x-rays by casting cesium iodide converter into the holes of a metal honeycomb structure and reading out by amorphous silicon diode array, as further described by their abstract: "One of the most promising new approaches for rapid portal imaging in radiation therapy are the large area digital detectors currently under development. These systems use a two-dimensional array of amorphous silicon (a:Si) diodes to generate an image and have several desirable aspects, including the ability to produce an image in real-time. A fundamental problem with current portal imaging devices is that the inherent x-ray photon detection sensitivity is small. When acceptable patient doses are used, this low sensitivity results in poor image quality due to limited image contrast resolution. This poor image quality limits the usefulness in patient care. "A key to achieving significant improvement in portal imaging is the use of a:Si with a high efficiency converter screen. We propose to develop a modified two-dimensional imaging system using a very thick segmented scintillator integrated with the a:Si detector to achieve this improvement. This has the potential to significantly improve the resulting image quality. Research will be carried out to produce large-area, thick segmented x-ray imaging converters with improved stopping power for high energy x-rays while providing a submillimeter spatial resolution. This method involves injection of the scintillator material into a metal collimater matrix. The proposed method overcomes limitations of standard fabrication procedures by producing a cost-effective technique of fabricating large-area segmented x-ray scintillators. "In the Phase I program, we shall concentrate on the research of producing high quality, limited area converters. In the Phase II program, the converter will be scaled up to portal imaging dimensions and incorporated into a fully functional a:Si imaging system." PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述：调查人员提议测试开发一种 浇注碘化铯提高高能X射线面阵探测器效率 转换成金属蜂窝结构的孔，并由 非晶硅二极管阵列，如其摘要进一步描述的： 最有希望的新方法之一，用于放射治疗中的快速门脉成像 治疗是目前正在开发的大面积数字探测器。这些 系统使用非晶硅(a：Si)二极管的二维阵列来 生成图像并具有几个所需的方面，包括能够 实时生成图像。当前门户的一个根本问题 成像设备的固有x射线光子探测灵敏度是 小的。当使用可接受的患者剂量时，这种低敏感度导致 由于图像对比度分辨率有限，图像质量较差。这个糟糕的形象 质量限制了患者护理的有用性。 实现门户成像显著改进的一个关键是使用 答：具有高效率转换屏的SI。我们建议开发一种改进的 采用超厚分段闪烁体的二维成像系统 与a：si探测器集成以实现这一改进。这件事有 有可能显著提高所产生的图像质量。研究将会 用于生产大面积、厚分段的X射线成像转换器 提高了高能X射线的阻挡能力，同时提供了 亚毫米空间分辨率。这种方法涉及到注入 将闪烁体材料制成金属准直器矩阵。建议的方法 克服了标准制造过程的限制，通过生产 高性价比的大面积分段X射线制作技术 闪烁体。 在第一阶段的计划中，我们将集中精力研究生产高 质量好、面积有限的转换器。在第二阶段计划中，转换器将 可扩展到门户图像尺寸并整合到完整的 功能a：硅成像系统。 建议的商业应用：不可用