基于GPI连接分子的全细胞肿瘤疫苗-猫眼课题宝

基于GPI连接分子的全细胞肿瘤疫苗

批准号：

6017968

负责人：

ANDREW H SEGAL

金额：

$10.52万

依托单位：

GENITRIX, LLC

依托单位国家：

美国

项目类别：

财政年份：

1999

资助国家：

美国

项目状态：

已结题

起止时间：

1999-07-01 至 2000-06-30

来源：

https://reporter.nih.gov/project-details/6017968

关键词：

antigen antibody reaction cell membrane chimeric proteins gene targeting glycosylphosphatidylinositols laboratory mouse neoplasm /cancer immunology neoplasm /cancer immunotherapy neoplasm /cancer vaccine neoplastic cell tissue /cell preparation vaccine development vector vaccine

项目摘要

项目成果

ANDREW H SEGAL的其他基金

相似基金

相关文献

中文摘要

翻译

点击翻译按钮获取中文摘要

英文摘要

DESCRIPTION: (Adapted from the applicant's abstract) A number of strategies are under development by various groups for the creation of therapeutic tumor vaccines using gene transfer into autologous cells. However, gene transfer entails a number of technical problems that limit both the clinical utility and commercial viability of such vaccines. As an alternative, this project will generate a chimeric glycosylphosphatidylinositol-linked molecule that facilitates early events in the afferent limb of the immune response. The utility of this molecule in the creation of tumor vaccines will be tested in mouse models PROPOSED COMMERCIAL APPLICTION: NOT AVAILABLE

期刊论文(0)

专著(0)

科研奖励(0)

会议论文