QUANTITATIVE PERFORMANCE ASSESSMENT OF THE AIDS DEMENTIA COMPLEX
QUANTITATIVE PERFORMANCE ASSESSMENT OF THE AIDS DEMENTIA COMPLEX
批准号:
6112303
负责人:
JOHN J SIDTIS
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-02-01 至 1999-01-31
关键词:
AIDS dementia complex AIDS therapy HIV infections attention audiometry auditory stimulus behavioral /social science research tag biomedical automation brain electrical activity cognition computer program /software disease /disorder classification electroencephalography evoked potentials human subject human therapy evaluation method development neuropsychological tests neuropsychology performance psychomotor reaction time stimulus /response visual stimulus
中文摘要
这个新项目试图扩展神经心理学的工作
英文摘要
This new project seeks to extend the work on neuropsychological
assessment accomplished in the Program's initial period of funding. Its
objective is to extend the current method of quantitative performance
evaluation of ADC, focussing on more sensitive measures that might prove
valuable in multidisciplinary studies directed at the underlying
pathophysiological mechanism of ADC. Starting with a well-standardized
procedure, this project will establish the utility of a Continuous
Performance Task (CPT), using a reaction time measure of sustained
attention to characterize ADC. The utility of CPT as a sensitive, early
measure of treatment effects in studies of anti-retroviral therapy and
of therapies directed at potential neuropathophysiological mechanisms of
ADC will also be studied. As a correlate of the CPT measure, its
corresponding event related potential (ERP) will also be studied with
respect to ADC. Both the CPT and event related potential measures will
be studied during FDG/PET scanning in collaboration with Project 4. The
objective of these studies is not to replace the previously established
methods of the neuropsychological assessment of ADC, but to develop more
sensitive measures of impairment in this syndrome that can play a
significant role in studying treatment effects and potential
pathophysiological mechanisms. In the context of this Program, these
studies will be integrated with the studies of regional cerebral
metabolism, quantitative MRI, and EEG power spectra, and will play an
important role in correlative studies using surrogate markers of direct
and indirect effects of HIV-1 infection of the CNS.
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CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7901185
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项目类别:
-
资助金额:$23.31万
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财政年份:2009
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负责人:JOHN J SIDTIS
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依托单位:
CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7788161
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项目类别:
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资助金额:$37.93万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
Cortical-Subcortical Interaction in PD and Normal Speech
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批准号:9037638
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项目类别:
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资助金额:$44.34万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
Cortical-Subcortical Interaction in PD and Normal Speech
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批准号:8451205
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项目类别:
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资助金额:$41.68万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7194257
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项目类别:
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资助金额:$36.47万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7390303
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项目类别:
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资助金额:$36.74万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
Cortical-Subcortical Interaction in PD and Normal Speech
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批准号:8642618
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项目类别:
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资助金额:$44.08万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
Cortical-Subcortical Interaction in PD and Normal Speech
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批准号:8320453
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项目类别:
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资助金额:$45.75万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
Cortical-Subcortical Interaction in PD and Normal Speech
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批准号:8827748
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项目类别:
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资助金额:$43.4万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7094753
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项目类别:
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资助金额:$37.14万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
CORTICAL-SUBCORTICAL INTERACTION IN PD AND NORMAL SPEECH
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批准号:7589731
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项目类别:
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资助金额:$37.52万
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财政年份:2006
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负责人:JOHN J SIDTIS
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依托单位:
QUANTITATIVE PERFORMANCE ASSESSMENT OF THE AIDS DEMENTIA COMPLEX
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批准号:6243636
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项目类别:
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资助金额:$17.37万
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财政年份:1997
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负责人:JOHN J SIDTIS
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依托单位:
AIDS DEMENTIA COMPLEX
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批准号:2830852
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项目类别:
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资助金额:$10.0万
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财政年份:1989
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负责人:JOHN J SIDTIS
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依托单位:
AIDS DEMENTIA COMPLEX
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批准号:2265642
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项目类别:
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资助金额:$85.36万
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财政年份:1989
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负责人:JOHN J SIDTIS
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依托单位:
AIDS DEMENTIA COMPLEX
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批准号:2332948
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项目类别:
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资助金额:$86.83万
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财政年份:1989
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负责人:JOHN J SIDTIS
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依托单位:
海外基金