TRAINING IN MOLECULAR AND CELLULAR CARDIOLOGY

分子和细胞心脏病学培训

• 批准号: 2857721
• 负责人: ALAN B WEDER
• 金额: $ 27.47万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-30 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2857721
• 关键词: TRAINING; MOLECULAR; CELLULAR; CARDIOLOGY

This application is for a new training grant in cardiovascular science at the University of Michigan. The long term objective of this program is to train postdoctoral M.D. and Ph.D. fellows for independent basic research careers in molecular and cellular cardiovascular science. This is an interdivisional and interdepartmental program incorporating the research interests and expertise of 20 faculty members in the Departments of Internal Medicine, Biological Chemistry, Human Genetics, Microbiology/Immunology, Pathology, Pharmacology, Physiology, Surgery and the Howard Hughes Medical Institute at the University of Michigan. The faculty preceptors of the program represent an outstanding group of molecular and cellular biologists whose research interests are divided into three related cardiovascular areas: 1) the regulation of gene expression in vascular cells with emphasis on understanding the molecular basis of cellular proliferation, thrombosis and inflammation, leading to vascular pathology; 2) the molecular mechanisms regulating gene expression in cardiac and skeletal muscle during normal development and in pathophysiological states; and 3) gene therapy for cardiovascular diseases. This training grant is administered through the Cardiovascular Research Center in the Department o Internal Medicine. The program is directed by Dr. Elizabeth G. Nabel, Program Director, and Dr. Seigo Izumo, Program Co-Director, both established investigators. Dr. Nabel directs the Cardiovascular Research Center, and Dr. Izumo is the Chief of the Division of Cardiology. The Training Program is supervised by an Internal Advisory Committee comprised of senior academicians and leaders at the University of Michigan. Trainees are M.D., M.D./Ph.D, or Ph.D. postdoctoral scientists. Four postdoctoral slots in the first year and a total of eight slots in years 2-5 are requested to support fellows pursuing fulltime basic research in cardiovascular science. Each trainee will commit to 2-3 years to research training. Ph.D. postdoctoral trainees will have longterm career interests in basic cardiovascular sciences. M.D. and M.D./Ph.D. trainees will have completed three years of residency training in Internal Medicine, as well as two years of clinical cardiology subspecialty training which is fully funded by the University of Michigan Hospital. M.D. trainees participate in a Postgraduate Research Training Program Course, an established three month introductory laboratory training course in molecular and cellular biology offered by the University of Michigan Medical School. The training program is strongly committed to increasing the number of women and underrepresented minority individuals who receive training in cardiovascular research. Facilities for research training include the Cardiovascular Research Center and the individual research laboratories of the 20 preceptors located at the University of Michigan Medical Center in MSRB III/MSRB II/MSRB I/MS I and II, encompassing 29,847 sq. ft. of research space in 5 contiguous buildings. Upon completion of the training program, trainees are guided to apply for independent research funding and to pursue careers as independent investigators in cardiovascular sciences at academic medical schools.

此申请适用于心血管方面的新培训补助金 密歇根大学的科学。的长期目标 该项目旨在培养博士后M.D.和Ph.D.研究员 分子和细胞领域的独立基础研究事业 心血管科学。 这是一个跨部门和 结合研究兴趣和的跨部门计划 内政部 20 名教职人员的专业知识 医学、生物化学、人类遗传学、 微生物学/免疫学、病理学、药理学、生理学、 外科和大学霍华德休斯医学院 密歇根州。该计划的教师导师代表了 杰出的分子和细胞生物学家群体 研究兴趣分为三个相关的心血管 领域：1）血管细胞基因表达的调控 强调了解细胞的分子基础 增殖、血栓形成和炎症，导致血管 病理; 2）调控基因表达的分子机制 在正常发育过程中的心肌和骨骼肌中以及在 病理生理状态； 3）心血管基因治疗 疾病。 该培训补助金通过心血管部门管理 内科研究中心。该计划 由项目总监 Elizabeth G. Nabel 博士和 Seigo Izumo，项目联合主任，两人都设立了调查员。 Nabel 博士负责心血管研究中心，Izumo 博士负责 现任心血管内科主任。培训计划是 由内部咨询委员会监督，该委员会由高级人员组成 密歇根大学的院士和领导人。 受训者是医学博士、医学博士/博士或哲学博士。博士后科学家。 第一年四个博士后名额，总共八个 要求 2-5 年的名额来支持研究员追求 全职从事心血管科学基础研究。每位练习生 将承诺2-3年的研究培训。博士博士后 学员将对基本的职业有长期的兴趣 心血管科学。医学博士和医学博士/博士受训者将有 完成了三年的内科住院医师培训， 以及两年的临床心脏病学亚专业培训 该项目由密歇根大学医院全额资助。医学博士 学员参加研究生研究培训计划 课程，为期三个月的入门实验室培训 大学提供的分子和细胞生物学课程 密歇根医学院。培训计划很给力 致力于增加妇女人数和代表性不足的人数 接受心血管培训的少数族裔 研究。 研究培训设施包括 心血管研究中心及个体研究 位于大学的20位导师的实验室 密歇根医疗中心 MSRB III/MSRB II/MSRB I/MS I 和 II， 包括 5 个连续的 29,847 平方英尺的研究空间 建筑物。培训计划完成后，学员将 指导申请独立研究经费并追求 作为心血管科学独立研究者的职业生涯 学术医学院。