TRAINING IN MOLECULAR AND CELLULAR CARDIOLOGY

这份申请是关于心血管疾病的新培训补助金 密歇根大学的科学。的长期目标 这个项目是培养博士后医学博士。和博士研究员为 分子和细胞的独立基础研究职业 心血管科学 这是一个跨部门和 跨部门计划，包括研究兴趣和 20名教师在内部部门的专业知识 医学，生物化学，人类遗传学， 微生物学/免疫学，病理学，药理学，生理学， 外科和大学的霍华德休斯医学研究所 密歇根州。该计划的教师代表了一个 一群杰出的分子和细胞生物学家 研究兴趣分为三个相关的心血管 领域：1）调控血管细胞中的基因表达， 强调理解细胞的分子基础 增殖，血栓形成和炎症，导致血管 病理学; 2）调节基因表达的分子机制 在正常发育期间的心肌和骨骼肌中， 病理生理状态; 3）心血管疾病的基因治疗 疾病 这项培训补助金通过心血管 内科研究中心。程序 由伊丽莎白·G博士指导。Nabel，项目总监和博士。 Seigo Izumo，项目联合主任，两人都成立了研究者。 博士Nabel是心血管研究中心的主任，Izumo博士 是心脏科的主任培训计划是 由内部咨询委员会监督， 密歇根大学的学者和领导人。 实习生是医学博士，医学博士/博士，或博士学位。博士后科学家 第一年有四个博士后名额， 要求在第2-5年提供名额，以支持研究员 心血管科学的全职基础研究。每个学员 将致力于2-3年的研究培训。博士博士后 学员将有长期的职业兴趣， 心血管科学M.D. M.D.博士学员将有 完成了三年的内科住院医师培训， 以及两年的临床心脏病学专科培训 完全由密歇根大学医院资助。M.D. 学员参加研究生研究培训计划 课程，为期三个月的入门实验室培训 大学开设的分子和细胞生物学课程 密歇根医学院该培训计划是强有力的 致力于增加妇女人数和任职人数不足 接受心血管训练的少数人 research. 研究训练设施包括 心血管研究中心和个人研究 位于大学的20个导师的实验室 密歇根州医疗中心MSRB III/MSRB II/MSRB I/MS I和II， 占地29，847平方米，英尺5个连续的研究空间 建筑培训课程结束后，学员将 指导申请独立研究基金， 作为心血管科学的独立研究者， 医学院校。

This application is for a new training grant in cardiovascular science at the University of Michigan. The long term objective of this program is to train postdoctoral M.D. and Ph.D. fellows for independent basic research careers in molecular and cellular cardiovascular science. This is an interdivisional and interdepartmental program incorporating the research interests and expertise of 20 faculty members in the Departments of Internal Medicine, Biological Chemistry, Human Genetics, Microbiology/Immunology, Pathology, Pharmacology, Physiology, Surgery and the Howard Hughes Medical Institute at the University of Michigan. The faculty preceptors of the program represent an outstanding group of molecular and cellular biologists whose research interests are divided into three related cardiovascular areas: 1) the regulation of gene expression in vascular cells with emphasis on understanding the molecular basis of cellular proliferation, thrombosis and inflammation, leading to vascular pathology; 2) the molecular mechanisms regulating gene expression in cardiac and skeletal muscle during normal development and in pathophysiological states; and 3) gene therapy for cardiovascular diseases. This training grant is administered through the Cardiovascular Research Center in the Department o Internal Medicine. The program is directed by Dr. Elizabeth G. Nabel, Program Director, and Dr. Seigo Izumo, Program Co-Director, both established investigators. Dr. Nabel directs the Cardiovascular Research Center, and Dr. Izumo is the Chief of the Division of Cardiology. The Training Program is supervised by an Internal Advisory Committee comprised of senior academicians and leaders at the University of Michigan. Trainees are M.D., M.D./Ph.D, or Ph.D. postdoctoral scientists. Four postdoctoral slots in the first year and a total of eight slots in years 2-5 are requested to support fellows pursuing fulltime basic research in cardiovascular science. Each trainee will commit to 2-3 years to research training. Ph.D. postdoctoral trainees will have longterm career interests in basic cardiovascular sciences. M.D. and M.D./Ph.D. trainees will have completed three years of residency training in Internal Medicine, as well as two years of clinical cardiology subspecialty training which is fully funded by the University of Michigan Hospital. M.D. trainees participate in a Postgraduate Research Training Program Course, an established three month introductory laboratory training course in molecular and cellular biology offered by the University of Michigan Medical School. The training program is strongly committed to increasing the number of women and underrepresented minority individuals who receive training in cardiovascular research. Facilities for research training include the Cardiovascular Research Center and the individual research laboratories of the 20 preceptors located at the University of Michigan Medical Center in MSRB III/MSRB II/MSRB I/MS I and II, encompassing 29,847 sq. ft. of research space in 5 contiguous buildings. Upon completion of the training program, trainees are guided to apply for independent research funding and to pursue careers as independent investigators in cardiovascular sciences at academic medical schools.