CHEMISTRY OF BIOLOGICAL SYSTEMS

生物系统化学

• 批准号: 2872579
• 负责人: BRUCE GANEM
• 金额: $ 20.12万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2872579
• 关键词: CHEMISTRY; BIOLOGICAL; SYSTEMS

This revised proposal describes plans by sixteen Cornell faculty members to establish a vigorous chemistry-biology interface predoctoral training program which is designed to produce scientists having thorough training in several aspects of "pure" chemistry as well as in scientific disciplines such as structural and bioorganic chemistry, drug design, enzymology and molecular biology (to name just a few) which lie at the interface of chemistry and biology. The proposed project focuses sharply on three main features of the chemistry of biological systems: design, assembly and analysis. The purpose of the plan described herein is to help trainees develop beyond the scope of a typical graduate program in chemistry. In addition to having strong undergraduate training in chemistry, the sixteen students selected for support will further advance their interdisciplinary training by planning their graduate academic work around a core curriculum of courses in areas spanning both chemical and biological disciplines. Moreover each will be completely free to carry out his or her doctoral thesis research in one or more of the laboratories of the sixteen participating faculty. All participating faculty have strong research programs in various aspects of chemistry, which are well-funded by the National Institutes of Health. Nine participating faculty have primary academic appointments in the Department of Chemistry, and five of these chemists are elected members of the field of biochemistry. The overall research interests of participating faculty are broadly distributed over areas of synthetic organic, bioorganic, biophysical and polymer chemistry, as well as such fields as x-ray crystallography, nmr spectroscopy, protein structure and function, enzymology and immunology. While individual research groups are extremely well-equipped to conduct the proposed research, Cornell University maintains a large number of diverse instrument facilities and dedicated research centers which are available to all trainees, Besides attending weekly seminars on relevant topics within the Field of Chemistry and the Division of Biological Sciences at Cornell, trainees will participate in a special interdisciplinary seminar program, with monthly meetings during the academic year when both students and faculty present their work. Trainees will also be exposed to industrial research through internships with interested industrial affiliates as well as through campus seminars and visits by industrial scientists. Thesis research and collaborations in the laboratories of the sixteen participating faculty members prepare trainees for careers in multidisciplinary research at the interface of chemistry and biology.

这份修订后的提案描述了康奈尔大学16名教职员工的计划。 建立生机勃勃的化学-生物接口博士前培养 旨在培养经过全面培训的科学家的计划 在“纯”化学和科学的几个方面 诸如结构和生物有机化学、药物设计、 酶学和分子生物学(仅举几个例子) 化学与生物的界面。拟议中的项目重点突出 关于生物系统化学的三个主要特征：设计， 组装和分析。本文所述计划的目的是 帮助实习生超越一般研究生课程的范围 化学反应。除了拥有强大的本科生培训外， 化学，16名被选中支持的学生将进一步晋级 通过计划他们的研究生学术工作进行跨学科培训 围绕着化学和化学领域的核心课程 生物学科。此外，每个人都将完全免费携带 他或她的博士论文研究在一个或多个 16个参赛教职员工的实验室。所有参与者 教职员工在化学的各个方面都有强大的研究计划， 这些项目得到了美国国立卫生研究院的大力资助。九 参与的教职员工在 化学系，其中五名化学家当选为成员 在生物化学领域。的总体研究兴趣 参与的教职人员广泛分布在综合科学领域 有机、生物有机、生物物理和聚合物化学等 X-射线结晶学、核磁共振光谱、蛋白质结构和 功能、酶学和免疫学。虽然个别研究小组正在 康奈尔大学非常有能力进行这项拟议的研究 大学拥有大量不同的仪器设施和 专门的研究中心，可供所有学员使用，此外 参加每周一次的关于以下领域相关主题的研讨会 康奈尔大学化学与生物科学系，实习生 将参加一个特别的跨学科研讨会项目， 学生和教职员工在学年期间每月举行会议 展示他们的作品。学员还将接触到工业研究。 通过在感兴趣的行业附属公司以及 通过校园研讨会和工业科学家的访问。论文 十六世纪实验室中的研究和合作 参与培训的教职员工为学员的职业生涯做准备 化学和生物学交界处的多学科研究。