CHEMISTRY OF BIOLOGICAL SYSTEMS

生物系统化学

• 批准号: 6150909
• 负责人: BRUCE GANEM
• 金额: $ 20.78万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6150909
• 关键词: CHEMISTRY; BIOLOGICAL; SYSTEMS

This revised proposal describes plans by sixteen Cornell faculty members to establish a vigorous chemistry-biology interface predoctoral training program which is designed to produce scientists having thorough training in several aspects of "pure" chemistry as well as in scientific disciplines such as structural and bioorganic chemistry, drug design, enzymology and molecular biology (to name just a few) which lie at the interface of chemistry and biology. The proposed project focuses sharply on three main features of the chemistry of biological systems: design, assembly and analysis. The purpose of the plan described herein is to help trainees develop beyond the scope of a typical graduate program in chemistry. In addition to having strong undergraduate training in chemistry, the sixteen students selected for support will further advance their interdisciplinary training by planning their graduate academic work around a core curriculum of courses in areas spanning both chemical and biological disciplines. Moreover each will be completely free to carry out his or her doctoral thesis research in one or more of the laboratories of the sixteen participating faculty. All participating faculty have strong research programs in various aspects of chemistry, which are well-funded by the National Institutes of Health. Nine participating faculty have primary academic appointments in the Department of Chemistry, and five of these chemists are elected members of the field of biochemistry. The overall research interests of participating faculty are broadly distributed over areas of synthetic organic, bioorganic, biophysical and polymer chemistry, as well as such fields as x-ray crystallography, nmr spectroscopy, protein structure and function, enzymology and immunology. While individual research groups are extremely well-equipped to conduct the proposed research, Cornell University maintains a large number of diverse instrument facilities and dedicated research centers which are available to all trainees, Besides attending weekly seminars on relevant topics within the Field of Chemistry and the Division of Biological Sciences at Cornell, trainees will participate in a special interdisciplinary seminar program, with monthly meetings during the academic year when both students and faculty present their work. Trainees will also be exposed to industrial research through internships with interested industrial affiliates as well as through campus seminars and visits by industrial scientists. Thesis research and collaborations in the laboratories of the sixteen participating faculty members prepare trainees for careers in multidisciplinary research at the interface of chemistry and biology.

这份修订后的提案描述了康奈尔大学16名教职员工的计划 建立一个充满活力的化学-生物学接口博士前培养 旨在培养受过全面培训的科学家的计划 在“纯”化学的几个方面以及在科学方面， 学科，如结构和生物有机化学，药物设计， 酶学和分子生物学（仅举几例）， 化学和生物学的界面。拟议的项目重点突出 生物系统化学的三个主要特征：设计， 组装和分析。本计划的目的是 帮助学员发展超出了典型的研究生课程的范围， 化学.除了有强大的本科培训， 化学，十六名学生选择支持将进一步推进 通过规划研究生学术工作进行跨学科培训 围绕课程的核心课程，在化学和 生物学科。此外，每一个将完全免费携带 他或她的博士论文研究在一个或多个 16个参与实验室。所有参与 教师在化学的各个方面都有很强的研究计划， 由美国国立卫生研究院资助。九 参与的教师有主要的学术任命， 化学系，其中五名化学家是当选成员 生物化学领域的最高权威。的整体研究兴趣 参与的教师广泛分布在合成领域， 有机、生物有机、生物物理和聚合物化学，以及诸如 X射线晶体学、核磁共振光谱学、蛋白质结构和 功能、酶学和免疫学。虽然个别研究小组 康奈尔大学非常有能力进行这项研究， 大学拥有大量不同的仪器设施， 专门的研究中心，提供给所有学员，此外， * 参加每周一次的有关专题的研讨会， 康奈尔大学化学和生物科学系，受训人员 将参加一个特殊的跨学科研讨会计划，与 在学年期间的每月会议，当学生和教师 介绍他们的工作。学员还将接触到工业研究 通过与感兴趣的工业附属公司实习，以及 通过校园研讨会和工业科学家的访问。论文 十六个实验室的研究和合作 参与的教员为学员的职业生涯做好准备， 在化学和生物学的界面上进行多学科研究。