Chemistry of Biological Systems

这份更新提案描述了继续建立强有力的化学-生物接口(CBI)的计划。 博士前培训计划，旨在培训基础有机和基础知识方面的科学家 生物化学以及化学和生物学交界处的科学学科。这个 该计划现已进入第九个年头，进一步推进了我们最有动力和最好的 通过将研究生的学术工作集中在跨领域的核心课程上来获得合格的学生 包括化学和生物学科。每名实习生可在以下地点开展博士论文研究 22个教员培训员的一个或多个实验室附属于以下九个参加 单元：化学和化学生物学，神经生物学和行为学，分子生物学和遗传学， 生物医学、化学和生物分子工程、微生物学和免疫学、植物 病理学、植物生物学和营养学。 所有参与的教员都有强大的研究计划，要么是化学方面的，要么是生物学方面的 有很强的化学联系，并且资金充足的生物学家。他们的整体研究 兴趣广泛分布在化学(合成有机、生物有机、生物物理、聚合物、X射线 结晶学和蛋白质组学)和生物学(蛋白质结构和功能、酶学、免疫学、信号 转导、趋化、寄主/病原体相互作用和遗传学)。CBI实习生在他们的 核心学科(通常是每周一次)在各自的单位，与教员一起参加一个特殊的月度活动 CBI研讨会项目，并每月组织CBI“文学午餐”。有两个附加功能区分了 康奈尔CBI项目。首先，学员每学期邀请、组织和主持CBI专题研讨会的演讲者。 其次，实习生需要参加生物技术、生命科学或制药方面的实习。 公司，通过这些公司，他们获得跨学科生物医学研究的机会和经验。

This renewal proposal describes plans to continue a vigorous chemistry-biology interface (CBI) predoctoral training program that is designed to train scientists in key aspects of fundamental organic and biological chemistry as well as in scientific disciplines at the interface of chemistry and biology. The program, now in its ninth year, further advances the interdisciplinary training of our most motivated and well- qualified students by focusing their graduate academic work around a core curriculum in areas spanning both chemical and biological disciplines. Each trainee may carry out his or her doctoral thesis research in one or more of the laboratories of the twenty two faculty trainers affiliated with the following nine participating units: Chemistry and Chemical Biology, Neurobiology and Behavior, Molecular Biology and Genetics, Biomedical Sciences, Chemical and Biomolecular Engineering, Microbiology and Immunology, Plant Pathology, Plant Biology and Nutritional Sciences. All participating faculty have strong research programs either in chemistry with strong biological connections or in biology with strong chemical connections and are well-funded. Their overall research interests are broadly distributed over chemistry (synthetic organic, bioorganic, biophysical, polymer, x-ray crystallography and proteomics) and biology (protein structure and function, enzymology, immunology, signal transduction, chemotaxis, host/pathogen interactions and genetics). CBI trainees attend seminars in their core disciplines (usually weekly) in their respective units, participate together with faculty in a special monthly CBI seminar program, and organize monthly CBI "literature lunches". Two additional features distinguish the Cornell CBI program. First, trainees invite, organize, and host special CBI seminar speakers each semester. Secondly, trainees are required to participate in internships in biotech, life science, or pharmaceutical companies, through which they gain exposure to, and experience in, interdisciplinary biomedical research.