Chemistry of Biological Systems

这一更新建议描述了计划继续一个充满活力的化学生物学接口（CBI） 博士前培训计划，旨在培养科学家在基本有机和 生物化学以及化学和生物学交界处的科学学科。的 计划，现在在其第九个年头，进一步推进了我们最积极和良好的跨学科培训， 通过将研究生的学术工作集中在核心课程， 化学和生物学科。每个实习生可以在以下地点进行博士论文研究： 一个或多个实验室的二十二个教师培训师附属于以下九个参与 单位：化学和化学生物学，神经生物学和行为，分子生物学和遗传学， 生物医学科学，化学和生物分子工程，微生物学和免疫学，植物 病理学、植物生物学和营养科学。 所有参与的教师都有很强的研究计划，无论是在化学与生物学强 或者在生物学上有很强的化学联系，并且资金充足。他们的整体研究 兴趣广泛地分布在化学（合成有机、生物有机、生物物理、聚合物、x射线 晶体学和蛋白质组学）和生物学（蛋白质结构和功能，酶学，免疫学，信号 转导、趋化性、宿主/病原体相互作用和遗传学）。CBI学员参加研讨会， 核心学科（通常每周）在各自的单位，参加与教师一起在一个特殊的每月 CBI研讨会计划，并组织每月CBI“文学午餐”。两个额外的特征区分了 康奈尔加调局项目首先，学员邀请，组织，并主持特别CBI研讨会发言人每学期。 其次，要求学员参加生物技术、生命科学或制药方面的实习 通过这些公司，他们获得了跨学科生物医学研究的接触和经验。

This renewal proposal describes plans to continue a vigorous chemistry-biology interface (CBI) predoctoral training program that is designed to train scientists in key aspects of fundamental organic and biological chemistry as well as in scientific disciplines at the interface of chemistry and biology. The program, now in its ninth year, further advances the interdisciplinary training of our most motivated and well- qualified students by focusing their graduate academic work around a core curriculum in areas spanning both chemical and biological disciplines. Each trainee may carry out his or her doctoral thesis research in one or more of the laboratories of the twenty two faculty trainers affiliated with the following nine participating units: Chemistry and Chemical Biology, Neurobiology and Behavior, Molecular Biology and Genetics, Biomedical Sciences, Chemical and Biomolecular Engineering, Microbiology and Immunology, Plant Pathology, Plant Biology and Nutritional Sciences. All participating faculty have strong research programs either in chemistry with strong biological connections or in biology with strong chemical connections and are well-funded. Their overall research interests are broadly distributed over chemistry (synthetic organic, bioorganic, biophysical, polymer, x-ray crystallography and proteomics) and biology (protein structure and function, enzymology, immunology, signal transduction, chemotaxis, host/pathogen interactions and genetics). CBI trainees attend seminars in their core disciplines (usually weekly) in their respective units, participate together with faculty in a special monthly CBI seminar program, and organize monthly CBI "literature lunches". Two additional features distinguish the Cornell CBI program. First, trainees invite, organize, and host special CBI seminar speakers each semester. Secondly, trainees are required to participate in internships in biotech, life science, or pharmaceutical companies, through which they gain exposure to, and experience in, interdisciplinary biomedical research.