COVERT PHYSIOLOGIC RECOGNITION IN ALCOHOLIC AMNESIA

酒精性健忘症的隐蔽生理识别

• 批准号: 3109394
• 负责人: RUSSELL M BAUER
• 金额: $ 5.88万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 1983
• 资助国家: 美国
• 起止时间: 1983-09-29 至 1987-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3109394
• 关键词: Wernicke Korsakoff syndrome; alcoholism /alcohol abuse; human subject; memory; memory disorders; neural information processing; neuropsychological tests; neuropsychology; stimulus /response

Recent neuropsychological and cognitive-psychological research with normals and brain-damaged subjects has indicated that overt processes of stimulus identification can be dissociated from covert processes of stimulus recognition. Several studies have revealed positive evidence of covert recognition (e.g., autonomic discrimination, rudimentay lexical categorization) in the absence of overt verbal identification. This suggests that there are covert aspects of information-processing which are neither directly nor accurately reflected in verbal report data. The overall objective of the proposed research is to determine whether similar dissociations characterize the memory-recognition performance of alcoholic amnesics and three groups of controls. It is known that alcoholic amnesics show memory benefit ("savings") in repeated presentations of tasks they do not overtly remember previously performing. In this context, the purpose of the proposed studies is to determine whether such patients can covertly "recognize" learned material that they have overtly forgotten. This will be approached by studying dissociations and correlations between autonomic and verbal recognition indices in alcoholic Korsakoff patients, nonalcoholic amnesics, long-term alcoholics, and normal controls. Four paradigms widely used in memory research (simple recognition, rate-of-forgetting, temporal-gradient remote memory assessment, and levels-of-processing) will be employed to study the relationship between verbal and autonomic (i.e., electrodermal) indices of recognition under differing conditions. If it is the case that, in alcoholic Korsakoff patients and controls, autonomic evidence of learning occurs in the absence of overt verbal report, then several critical issues are raised. First, amnesic failures in memory paradigms may be more related to deficits in demonstrating knowledge than to having knowledge about learned stimuli. Second, the question, "does the patient remember" may be answered in different ways depending upon which response system is used to index memory performance. Third, the relationship between covert and overt recognition indices will have to be accounted for in theoretic models of amnesic memory defects.

正常人的神经心理学和认知心理学研究进展 大脑受损的受试者表明， 认同可以从刺激的内隐过程中分离出来 识别. 几项研究揭示了隐蔽的积极证据， 识别（例如，自主性词汇辨别 分类）在没有明显的口头识别。 这 这表明，有隐蔽方面的信息处理， 既不直接也不准确地反映在口头报告数据中。 的 拟议研究的总体目标是确定是否类似 解离表征了酗酒者的记忆-识别性能 遗忘组和三组对照组。 众所周知，酒精健忘症患者 在重复呈现他们所做的任务时显示记忆益处（“节省”） 不记得以前的表演。 在这方面， 这项研究的目的是确定这些患者是否可以秘密地 “承认”他们已经公开忘记的学习材料。 这将 通过研究自主神经之间的分离和相关性来接近 和语言识别指数， 非酒精性失忆者、长期酗酒者和正常对照组。 四 广泛用于记忆研究的范例（简单识别， 遗忘率、时间梯度远程记忆评估，以及 水平的处理）将被用来研究之间的关系， 言语和自主（即，皮肤电）识别指数 不同的条件。 如果是这样的话，在酗酒的科萨科夫 患者和对照组，自主学习的证据发生在没有 公开的口头报告，然后提出了几个关键问题。 第一、 记忆范式中的健忘症失败可能与以下缺陷更相关： 而不是拥有关于学习刺激的知识。 第二，“病人记得吗”这个问题可以在 不同的方式取决于使用哪种响应系统来索引存储器 性能 第三，内隐认知与外显认知的关系 在健忘症记忆的理论模型中， 缺陷