Validation of a commercial Helminth Viability Screening Assay for drug discovery against parasites of veterinary importance

验证商业 Helminth 活力筛选试验，用于针对具有兽医重要性的寄生虫的药物发现

• 批准号: BB/I532937/1
• 负责人: Karl Hoffmann
• 金额: $ 14.56万
• 依托单位: Aberystwyth University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FI532937%2F1
• 关键词: Validation; commercial; Helminth; Viability; Screening

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7.

• DOI: 10.1371/journal.pntd.0003593
• 发表时间: 2015-03
• 期刊: PLoS neglected tropical diseases
• 影响因子: 3.8
• 作者: Reimers N;Homann A;Höschler B;Langhans K;Wilson RA;Pierrot C;Khalife J;Grevelding CG;Chalmers IW;Yazdanbakhsh M;Hoffmann KF;Hokke CH;Haas H;Schramm G
• 通讯作者: Schramm G

The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica.

• DOI: 10.1371/journal.pntd.0003604
• 发表时间: 2015-03
• 期刊: PLoS neglected tropical diseases
• 影响因子: 3.8
• 作者: Edwards J;Brown M;Peak E;Bartholomew B;Nash RJ;Hoffmann KF
• 通讯作者: Hoffmann KF