Probe-free biophysical force and torque measurements with optical tweezers

使用光镊进行无探针生物物理力和扭矩测量

• 批准号: DP180101002
• 负责人: Prof Halina Rubinsztein-Dunlop
• 金额: $ 29.15万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2022-06-20
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180101002
• 关键词: Probe; free; biophysical; force; torque

This project aims to develop probe-free biophysical force and torque measurement methods based on optical tweezers. Many areas of research in cell biology are hampered by a lack of quantitative force measurements. This project aims to provide accurate quantitative measurements to enable in-depth understanding of forces at work during cell division, properties of blood cells and sperm motility which could generate further research leading to health benefits.

该项目旨在开发基于光学镊子的无探头生物物理力和扭矩测量方法。细胞生物学的许多研究领域由于缺乏定量的力测量而受到阻碍。该项目旨在提供准确的定量测量，以深入了解细胞分裂过程中的作用力、血细胞的特性和精子的运动性，从而产生进一步的研究，从而对健康产生好处。