Vaccines as drivers of disease emergence: transmission ecology and virulence evolution in Marek's disease

疫苗作为疾病出现的驱动因素：马立克氏病的传播生态学和毒力进化

• 批准号: BB/K011057/1
• 负责人: Venugopal Nair
• 金额: $ 126.4万
• 依托单位: The Pirbright Institute
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK011057%2F1
• 关键词: Vaccines; drivers; disease; emergence; transmission

See Lead Investigator application to NSF

参见向NSF提交的首席研究员申请

项目成果

Replication defective adenovirus serotype 5 expressing Marek's disease virus envelope glycoprotein as a potential Marek's disease vaccine in chicken

表达马立克氏病病毒包膜糖蛋白的复制缺陷腺病毒血清型 5 作为潜在的鸡马立克氏病疫苗

• 发表时间: 2016
• 期刊: Journal of Veterinary Medicine and Research
• 作者: Baigent SJ

Pervasive Differential Splicing in Marek's Disease Virus can Discriminate CVI-988 Vaccine Strain from RB-1B Very Virulent Strain in Chicken Embryonic Fibroblasts.

马立克氏病病毒中普遍存在的差异剪接可以在鸡胚胎成纤维细胞中区分 CVI-988 疫苗株和 RB-1B 强毒株。

• DOI: 10.3390/v12030329
• 发表时间: 2020
• 期刊: Viruses
• 作者: Sadigh Y

Pervasive differential splicing in Marek's Disease Virus can discriminate CVI-988 vaccine strain from RB-1B virulent strain in chicken embryonic fibroblasts

马立克氏病病毒中普遍存在的差异剪接可以区分鸡胚成纤维细胞中的 CVI-988 疫苗株和 RB-1B 强毒株

• DOI: 10.1101/723114
• 发表时间: 2019
• 作者: Sadigh Y

Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens.

• DOI: 10.1371/journal.pbio.1002198
• 发表时间: 2015-07
• 期刊: PLoS biology
• 影响因子: 9.8
• 作者: Read AF;Baigent SJ;Powers C;Kgosana LB;Blackwell L;Smith LP;Kennedy DA;Walkden-Brown SW;Nair VK
• 通讯作者: Nair VK