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ISOLATION OF A HODGKIN-RELATED ANTIBODY

ISOLATION OF A HODGKIN-RELATED ANTIBODY
霍奇金相关抗体的分离
批准号:
3174036
负责人:
CLIVE R TAYLOR
金额:
$12.72万
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-07-01 至 1987-06-30

项目摘要

项目成果

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中文摘要
翻译
我们已经获得了四种人类抗体,它们与各种不同的 组织切片中的人类细胞类型,包括里德·斯特恩伯格细胞。 我们已经开始生产足够数量的抗体, 不含小鼠免疫球蛋白,用于直接生物素化研究;以及 F(Ab)2试剂的制备我们还获得了一份T&B小组 细胞系和Poppema‘s Reed Sternberg细胞系,并已开始 这些抗体的特性与这些细胞系与静脉到 抗原分离。(2)
英文摘要
We have obtained four human antibodies that show reactivity with a variety of human cell types in tissue sections, including Reed Sternberg cells. We have commenced production of these antibodies in sufficient amounts, free of mouse immunoglobulin, for direct biotinylation studies; and preparation of F(ab)2 reagents. We have also obtained a panel of T&B cell lines and Poppema's Reed Sternberg cell lines, and have commenced characterization of those antibodies with those cell lines with a vein to antigen isolation. (2)
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