An automated 3D electron microscopy facility

自动化 3D 电子显微镜设备

• 批准号: LE150100004
• 负责人: Prof Eric Hanssen
• 金额: $ 36.01万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE150100004
• 关键词: automated; 3D; electron; microscopy; facility

An automated 3D electron microscopy facility: The aim of this project is to establish the next generation of electron microscopy facility, with a fully automated tool enabling 3D imaging. The automated serial section system incorporated in a scanning electron microscope circumvents the limitation of transmission electron microscopy, which provides unique insights into molecular structures and cell components at high resolution, however, the area and volume are limited in size to a few microns. This new type of microscope can image whole organisms and be used by non-electron microscopists. It will be housed in an open access facility and will meet a growing demand for 3D electron microscopy.

自动化3D电子显微镜设施：该项目的目的是建立下一代电子显微镜设施，使用全自动工具实现3D成像。扫描电子显微镜中集成的自动连续切片系统规避了透射电子显微镜的限制，它以高分辨率提供了对分子结构和细胞成分的独特见解，然而，面积和体积的大小仅限于几微米。这种新型显微镜可以对整个生物体成像，非电子显微镜专家也可以使用。它将被安置在一个开放获取的设施中，并将满足对3D电子显微镜日益增长的需求。