The mechanics of the collagen fibrillar network in ageing cartilage

老化软骨中胶原纤维网络的力学

• 批准号: BB/R004773/1
• 负责人: Nicholas Terrill
• 金额: $ 4.76万
• 依托单位: Diamond Light Source
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FR004773%2F1
• 关键词: mechanics; collagen; fibrillar; network; ageing

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Reduction of fibrillar strain-rate sensitivity in steroid-induced osteoporosis linked to changes in mineralized fibrillar nanostructure.

• DOI: 10.1016/j.bone.2019.115111
• 发表时间: 2019-11
• 期刊: Bone
• 影响因子: 4.1
• 作者: L. Xi;L. Xi;P. D. Falco;P. D. Falco;E. Barbieri;A. Karunaratne;L. Bentley;C. T. Esapa;G. R. Davis;Nicholas J. Terrill;R. Cox;N. Pugno;N. Pugno;N. Pugno;R. V. Thakker;R. Weinkamer;Wenwang Wu;D. Fang;D. Fang;H. S. Gupta

Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging.

• DOI: 10.3390/ma15051836
• 发表时间: 2022-03-01
• 期刊: Materials (Basel, Switzerland)
• 作者: Zhang Y;Hollis D;Ross R;Snow T;Terrill NJ;Lu Y;Wang W;Connelly J;Tozzi G;Gupta HS
• 通讯作者: Gupta HS

Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage.

• DOI: 10.1016/j.actbio.2021.09.037
• 发表时间: 2021-12
• 期刊: Acta biomaterialia
• 影响因子: 9.7
• 作者: Inamdar SR;Prévost S;Terrill NJ;Knight MM;Gupta HS
• 通讯作者: Gupta HS

Tomographic X-ray scattering based on invariant reconstruction: analysis of the 3D nanostructure of bovine bone.

• DOI: 10.1107/s1600576721000881
• 发表时间: 2021-04-01
• 期刊: Journal of applied crystallography
• 影响因子: 6.1
• 作者: De Falco P;Weinkamer R;Wagermaier W;Li C;Snow T;Terrill NJ;Gupta HS;Goyal P;Stoll M;Benner P;Fratzl P
• 通讯作者: Fratzl P

Collagen pre-strain discontinuity at the bone-Cartilage interface.

• DOI: 10.1371/journal.pone.0273832
• 发表时间: 2022
• 期刊: PloS one
• 影响因子: 3.7