NUTRITIONAL FACTORS IN AGE RELATED OCULAR DISORDERS

这项研究是比弗坝眼科研究的一个辅助项目， 已获得资助，调查与年龄有关的 眼科疾病及其与潜在危险因素的关系 该社区的老年人口（约4，800人） 人）。 眼睛研究的资金并不支持 营养因素的调查，其中一些可能发挥作用， 在白内障和黄斑变性的发展中起作用。 以前没有发表过流行病学研究， 对这些协会进行了全面评估。 我们建议估计17个主要 一半的老年人的营养和酒精 比弗坝（约4,800人）的饮食评估 采访了两年半。 从这上面取的血样 将对人群进行分析，以衡量潜在的 重要的营养素，膳食摄入量估计是 难以获得或不足以评估营养素 status. 我们将记录营养素的可靠性和有效性 使用饮食史估计老年人的摄入量 调查问卷由国家癌症研究所开发。 这 调查问卷的管理成本较低， 其他饮食评估方法，也可能提供一个更好的 长期营养摄入指数。

The proposed study is an adjunct to the Beaver Dam Eye Study which has received funding to investigate the prevalence of age-related eye diseases and their relationships to potential risk factors in the older adult population of this community (approximately 4,800 people). Funding for the eye study does not provide support for the investigation of nutritional factors, several of which may play roles in the development of cataract and macular degeneration. There have been no previous epidemiological studies published which have comprehensively evaluated these associations. We propose to estimate past and present intake of 17 major nutrients and alcohol from one-half of the older adult population of Beaver Dam (approximately 4,800 people) from dietary assessment interviews over a period of 2 1/2 years. Blood samples from this population will be analyzed to measure levels of potentially important nutrients for which dietary intake estimates are difficult to obtain or are inadequate measures to evaluate nutrient status. We will document the reliability and validity of nutrient intake estimates in older adults using the diet history questionnaire developed by the National cancer Institute. This questionnaire is less costly and time consuming to administer than other methods of dietary assessment and may also provide a better index of nutrient intake over an extended period of time.