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Development of Computational Models to Design Upper-Room Ultraviolet Germicidal Irradiation Air Disinfection Systems in Hospital Environments

开发计算模型来设计医院环境中的上室紫外线杀菌辐射空气消毒系统

基本信息

批准号：
EP/G008663/1
负责人：
Catherine Noakes
金额：
$ 32.26万
依托单位：
University of Leeds
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2009
资助国家：
英国
起止时间：
2009 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FG008663%2F1
关键词：
Development Computational Models Design Upper

项目摘要

Ultraviolet Germicidal Irradiation (UVGI) irradiation has been known for many years to have a lethal effect on microorganisms. It is routinely used in water disinfection and can be a viable method of reducing airborne pathogens in indoor environments to decrease the risk of cross transmission of infection. Despite recommendations for use in high risk healthcare environments such as tuberculosis (TB) wards, the application of UVGI remains limited due to lack of evidence gained directly in clinical settings. However two major clinical studies that are about to be published will prove the effectiveness of UVGI devices against TB transmission and thus a significant increase in the future demand for UVGI air disinfection is anticipated. To translate these clinical based research findings into successful control strategies tailored to the needs of a particular healthcare environment, robust guidance on designing safe and effective UVGI air disinfection systems is now needed. This project aims to address this need by developing a design tool for simulating the behaviour of upper room air disinfection devices in realistic hospital environments, and guidance documents to enable hospital managers, architects and engineers to (a) determine if UVGI disinfection is suitable for a particular environment and (b) to ensure any UVGI installations are both effective and safe. The proposed study will use computational fluid dynamics (CFD) simulations to carry out a parametric study quantifying the factors that influence the performance of a UV device to produce an empirical model of UVGI disinfection within a ventilation design model. The model will quantify the mean effectiveness, as well as stochastic variations, and provide an output in terms of UV device performance and relative risk of infection for ward occupants. This will enable better design and specification of UVGI systems without the use of resource intensive CFD models. Parametric studies using CFD models and the new design tool will then be used to draft three design guidance documents; suitability of upper-room UVGI systems in healthcare environments, safe installation and operation of UVGI systems, and optimising UVGI system design to minimise airborne infection risk.

多年来，人们都知道紫外线杀菌照射 (UVGI) 照射对微生物具有致命作用。它通常用于水消毒，是减少室内环境中空气传播的病原体以降低感染交叉传播风险的可行方法。尽管建议在结核病房等高风险医疗环境中使用 UVGI，但由于缺乏直接在临床环境中获得的证据，UVGI 的应用仍然受到限制。然而，即将发表的两项主要临床研究将证明 UVGI 设备对抗结核病传播的有效性，因此预计未来对 UVGI 空气消毒的需求将显着增加。为了将这些基于临床的研究结果转化为适合特定医疗环境需求的成功控制策略，现在需要设计安全有效的 UVGI 空气消毒系统的强有力的指导。该项目旨在通过开发一种设计工具来模拟真实医院环境中上层房间空气消毒设备的行为，并开发指导文件来满足这一需求，使医院管理人员、建筑师和工程师能够（a）确定 UVGI 消毒是否适合特定环境以及（b）确保任何 UVGI 安装既有效又安全。拟议的研究将使用计算流体动力学 (CFD) 模拟来进行参数研究，量化影响紫外线设备性能的因素，以在通风设计模型中生成 UVGI 消毒的经验模型。该模型将量化平均有效性以及随机变化，并提供紫外线设备性能和病房占用者感染相对风险方面的输出。这将有助于更好地设计和规范 UVGI 系统，而无需使用资源密集型 CFD 模型。使用 CFD 模型和新设计工具的参数研究将用于起草三份设计指导文件；上层房间 UVGI 系统在医疗保健环境中的适用性、UVGI 系统的安全安装和操作以及优化 UVGI 系统设计以最大程度地降低空气传播感染风险。