INFANT HEAT LOSS DETERMINED BY INFRARED THERMOGRAPHY

这项研究的长期目标是提供有价值的 婴幼儿热量损失和能量消耗的相关信息 各种环境和临床条件，目标是 改善新生儿管理，降低发病率和死亡率。 本研究的具体目的是：(1)对红外进行改性 热像图作为一种无创、快速、准确的新方法 测量婴儿的热量损失，因此能量消耗，(2)到 验证新方法，红外热像仪，通过比较它与 建立了测定婴儿能量消耗的方法， 间接量热法，以及(3)确定能量的差异 在子宫内暴露于药物滥用的婴儿与 新生儿期和前三个月未接触过的婴儿 几个月的生命。已经设计了三个实验来实现这些 目标。首先，正常新生儿(n=25)，低出生体重(n=15)， 低出生体重儿(n=10)将使用红外线进行研究 热像仪来确定能量消耗，以及辐射、对流、 蒸发性和传导性热损失。热损失方程式将会是 修改为计算不同出生婴儿的能量消耗 体重和胎龄。第二，能源支出将是 正常出生体重测定(n=10)，低出生体重孵化 (n=10)和未孵化(n=10)，孵化极低出生体重 10例婴幼儿同时红外热像仪和间接热像仪 量热法。这项研究将确定红外线的有效性 体温成像以量化这类婴儿的能量消耗，这是 这是住院婴儿人群的典型特征。第三，能源 将确定滥用药物母亲所生婴儿的支出 (n-20)在0、4、8和12周时。能源支出将是 无毒母亲所生婴儿(n-20)的检测结果 根据出生体重和出生体重与接触毒品的婴儿配对 胎龄组。红外热像仪可能是一种有用的临床应用 和研究婴儿热量损失的研究工具。使用它可能会导致 更好的婴儿护理，以及更准确的婴儿预测 能量消耗和体温调节能力。这项新技术的使用 一项信息研究中的技术将确定接触药物的婴儿 展示能源消耗的变化，一个不明而重要的 临床问题。

The long term objective of this research is to provide valuable information on heat loss and energy expenditure in infants under a variety of environmental and clinical conditions, with the goal of improving neonatal management and decreasing morbidity and mortality. The specific aims of this research are (1) to modify infrared thermography as a non-invasive, instant and accurate new method of measuring heat loss, and thus energy expenditure in infants, (2) to validate the new method, infrared thermography, by comparing it with an established method of determining energy expenditure in infants, indirect calorimetry, and (3) to determine if differences in energy expenditure are found in infants exposed to drug abuse in utero vs. unexposed infants both during the neonatal period and the first three months of life. Three experiments have been designed to achieve these aims. First, normal newborns (n=25), low birth weight (n=15), and very low birth weight (n=10) infants will be studied using infrared thermography to determine energy expenditure, and radiant, convective, evaporative and conductive heat losses. Heat loss equations will be modified to calculate energy expenditure in infants of varying birth weight and gestational age. Second, energy expenditure will be determined in normal birth weight (n=10), low birth weight incubated (n=10) and non-incubated (n=10), and incubated very low birth weight (n=10) infants by concurrent infrared thermography and indirect calorimetry. This study will determine the validity of infrared thermography to quantify energy expenditure in such infants, which are typical of the hospitalized infant population. Third, energy expenditure will be determined in infants born to drug abusing mothers (n--20) at 0, 4, 8 and 12 weeks of life. Energy expenditure will be determined in matched control infants born to drug-free mothers (n--20) paired with drug-exposed infants on the basis of birth weight and gestational age group. Infrared thermography may be a useful clinical and research tool for studying infant heat loss. Its use may result in better infant care, as well as more accurate predictions of infant energy expenditure and thermoregulatory ability. The use of this new technique in an informative study will determine if drug-exposed infants exhibit changes in energy expenditure, an unidentified and important clinical problem.