PHYSIOLOGY OF EXCITABLE MEMBRANES
PHYSIOLOGY OF EXCITABLE MEMBRANES
批准号:
3393291
负责人:
JOHN W MOORE
金额:
$21.95万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-09-01 至 1988-09-24
关键词:
anesthetics axon computer simulation electrical potential mathematical model membrane permeability membrane potentials neural conduction neural facilitation neural initiation neural transmission neurochemistry neurons neuropharmacology neurophysiology nuclear magnetic resonance spectroscopy saltwater environment synapses temperature jump
中文摘要
我们的目标是了解可兴奋细胞的功能,重点是
在神经元上,在膜和细胞水平上。
我们使用电压钳来研究电势模式对膜的影响
正常介质中的电导以及发生物理变化或化学变化时的电导
已添加代理。我们试图包含这些观察结果(以及其他人的观察结果)
变成了一个改进的数学模型。
在细胞水平上,我们正在研究几何和膜的变化
影响脉冲传导。
英文摘要
Our objective is to understand the functioning of excitable cells, with emphasis
on neurons, at the membrane and cellular levels.
We use the voltage clamp to study the effect of potential patterns on membrane
conductances in normal media and when physical changes are made or chemical
agents added. We seek to encompass these observations (and those of others)
into an improved mathematical model.
At the cellular level we are investigating how geometrical and membrane changes
affect impulse conduction.
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会议论文
CONDITIONED RESPONSE TIMING AND INTEGRATION
-
批准号:6165212
-
项目类别:
-
资助金额:$10.82万
-
财政年份:1998
-
负责人:JOHN W MOORE
-
依托单位:
CONDITIONED RESPONSE TIMING AND INTEGRATION
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批准号:2883458
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项目类别:
-
资助金额:$10.81万
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财政年份:1998
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负责人:JOHN W MOORE
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依托单位:
CONDITIONED RESPONSE TIMING AND INTEGRATION
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批准号:2452654
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项目类别:
-
资助金额:$12.15万
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财政年份:1998
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负责人:JOHN W MOORE
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依托单位:
ELECTROCHEMICAL SIGNALING IN VERTEBRATE PHOTORECEPTORS
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批准号:3264008
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项目类别:
-
资助金额:$19.89万
-
财政年份:1987
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
-
批准号:3393292
-
项目类别:
-
资助金额:$12.65万
-
财政年份:1978
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
-
批准号:3393289
-
项目类别:
-
资助金额:$19.54万
-
财政年份:1978
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
-
批准号:3393290
-
项目类别:
-
资助金额:$19.71万
-
财政年份:1978
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
-
批准号:2260142
-
项目类别:
-
资助金额:$16.41万
-
财政年份:1978
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
-
批准号:3393293
-
项目类别:
-
资助金额:$15.69万
-
财政年份:1978
-
负责人:JOHN W MOORE
-
依托单位:
PHYSIOLOGY OF EXCITABLE MEMBRANES
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批准号:3393287
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项目类别:
-
资助金额:$16.11万
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财政年份:1978
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负责人:JOHN W MOORE
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依托单位:
海外基金