CONSEQUENCES OF PROXIMAL GIANT AXON FORMATIONS

外周感觉神经末梢似乎比运动神经末梢更敏感 与某些药剂的神经毒性作用相对应。 内的一处病变 这些神经的脊髓终止，对应于外周神经中的脊髓终止 终端，会导致本体感受信息的不正确整合 脊髓突触的神经元从而造成了周围神经的缺陷 初级传入 将在患有神经病的猫中研究终末功能，包括 丙烯酰胺或阿霉素。 具体来说，突触subserving节段反射 脊髓小脑背侧束的起源细胞将 电生理学评估。 这些数据将与那些 形态学研究，试图确定脊髓的贡献 缺陷导致周围神经病的临床体征。

Peripheral sensory nerve terminals appear more susceptible than their motor counterparts to the neurotoxic effects of certain agents. A lesion in the spinal cord termination of these nerves, corresponding to that in the peripheral terminals, would result in incorrect integration of proprioceptive information at spinal synapses and thus compound the peripheral defect. Primary afferent terminal function will be investigated in cats with neuropathies included by acrylamide or doxorubicin. Specifically, synapses subserving segmental reflexes and the cells of origin of the dorsal spinocerebellar tracts will be electrophysiologically evaluated. These data will be correlated with those with morphological studies in an attempt to ascertain the contribution of spinal cord defects make to the clinical signs of the peripheral neuropathies.