FASEB CONFERENCES: MOLECULAR ASPECTS OF METASTASIS

最近，该领域取得了许多令人振奋的进展 转移的可能性。只有有限的会议或没有会议 强调转移的分子方面，特别是 在考虑更受欢迎和宣传的会议时。 目前还没有关于卵巢癌转移的深入会议 以下一系列会议：戈登会议，ICN- 加州大学洛杉矶分校(尽管计划在今年冬天举行)，FASEB夏季 会议，以及细胞生物学学会会议(尽管 关于肿瘤生物学和转移的区域会议的数量， 主要从生物学的角度来看已经发生)。这 会议将通过聚焦于分子方面而脱颖而出 与肿瘤转移有关的各种过程。曾经有过 许多会议都在讨论转移问题，但其中许多会议 太多时候，我都在处理生物学问题，同样的 由相同的个人提交的材料。癌基因、生长 影响生长的因素、抑制因素及其相互关系 这些区域与转移高度相关，并将 讨论过。另一次会议将处理耐药突变株 了解遗传调节、分化、肿瘤 进展、异质性和转移。其他课程将 新分子在影响免疫中的作用 系统，特别是用IL-2、层粘连蛋白、 纤维连接蛋白和蛋白多糖。其他演示文稿将涵盖 细胞基质的分子组成，分子的性质 这些分子的细胞受体，这些分子是如何调节的 转移、肿瘤侵袭与参与肿瘤的蛋白水解酶 入侵。最后，可以促进肿瘤细胞生长的特定分子 将介绍运动性和血管生成。预计 对生物学分子方面的基本关注，与 转移将使这次会议成为一次富有成效和有趣的会议。

Numerous exciting advances have been made recently in the field of metastasis. There have been limited or no conferences emphasizing the molecular aspects of metastasis, particularly when considering the more popular and advertised conferences. There have been no in-depth conferences on metastasis in the following series of conferences: the Gordon Conferences, ICN- UCLA (though one is scheduled this winter), FASEB Summer Conferences, and Cell Biology Society Conferences (though a number of regional conferences on tumor biology and metastasis, principally from a biological point of view have occurred). This conference will distinguish itself by focusing on molecular aspects of various processes involved in metastasis. There have been many conferences dealing with metastasis but many of these have all too often been dealing with the biology, with the same material presented by the same individuals. Oncogenes, growth factors, factors that inhibit growth and interrelationship among these are areas highly relevant to metastasis and will be discussed. Another session will deal with drug-resistant mutants in understanding genetic regulation, differentiation, tumor progression, heterogeneity and metastasis. Other sessions will cover the role of novel molecules in influencing the immune system, particularly stimulation of LAK cells with IL-2, laminin, fibronectin and proteoglycans. Other presentations will cover the molecular components of the cell matrix, the molecular nature of cell receptors for these molecules, how these modulate metastasis, tumor invasion and proteases involved in tumor invasion. Finally, specific molecules that can promote tumor cell motility and angiogenesis will be presented. It is anticipated that a fundamental focus on molecular aspects of biology related to metastasis will make this a productive and interesting conference.