Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis
Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis
批准号:
nhmrc : 570768
负责人:
A/Pr James Triccas
金额:
$36.54万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Two million people die from tuberculosis (TB) each year. The immune system is unable to eradicate the TB bacterium, and the type of immune response needed to protect against the disease is poorly understood. We will use animal models of TB infection and sophisticated immunological techniques to decipher how the TB bacterium interacts with the immune sytem and causes disease. We will also develop new TB vaccines that aim to boost the immune response in the lung, the main site of TB infection.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Multistage vaccines for the prevention of tuberculosis
-
批准号:nhmrc : 1102597
-
项目类别:Project Grants
-
资助金额:$60.84万
-
财政年份:2016
-
负责人:A/Pr James Triccas
-
依托单位:
A new class of inhibitors for the treatment of tuberculosis
-
批准号:nhmrc : 1084266
-
项目类别:Project Grants
-
资助金额:$48.06万
-
财政年份:2015
-
负责人:A/Pr James Triccas
-
依托单位:
New candidate vaccines to prevent tuberculosis: preclinical assessment of efficacy, safety and mechanism of protection
-
批准号:nhmrc : 1043519
-
项目类别:Project Grants
-
资助金额:$39.62万
-
财政年份:2013
-
负责人:A/Pr James Triccas
-
依托单位:
Genes of Mycobacterium tuberculosis essential for Latent Tuberculosis Infection
-
批准号:nhmrc : 1051246
-
项目类别:Project Grants
-
资助金额:$39.35万
-
财政年份:2013
-
负责人:A/Pr James Triccas
-
依托单位:
Tuberculosis control:from discovery to public health practice and policy
-
批准号:nhmrc : 1043225
-
项目类别:Centres of Research Excellence
-
资助金额:$174.14万
-
财政年份:2012
-
负责人:A/Pr James Triccas
-
依托单位:
Impact of Influenza A infection on T cell-mediated immunity to pulmonary tuberculosis.
-
批准号:nhmrc : 1011027
-
项目类别:NHMRC Project Grants
-
资助金额:$32.54万
-
财政年份:2011
-
负责人:A/Pr James Triccas
-
依托单位:
Visualisation of gamma-delta T cell responses in cutaneous inflammation
-
批准号:nhmrc : 632706
-
项目类别:NHMRC Project Grants
-
资助金额:$38.07万
-
财政年份:2010
-
负责人:A/Pr James Triccas
-
依托单位:
Regulation of pulmonary immune responses to subunit vaccines against tuberculosis
-
批准号:nhmrc : 512269
-
项目类别:NHMRC Project Grants
-
资助金额:$33.95万
-
财政年份:2008
-
负责人:A/Pr James Triccas
-
依托单位:
Identifying determinants of mycobacterial pathogenesis and understanding host immunity for devel. of novel anti-TB vaccine
-
批准号:nhmrc : 402737
-
项目类别:Career Development Fellowships
-
资助金额:$31.73万
-
财政年份:2006
-
负责人:A/Pr James Triccas
-
依托单位:
Manipulating immunity to Mycobacterium tuberculosis with novel vaccines and immunotherapeutics
-
批准号:nhmrc : 402728
-
项目类别:NHMRC Project Grants
-
资助金额:$34.99万
-
财政年份:2006
-
负责人:A/Pr James Triccas
-
依托单位:
Molecular approaches to developing subunit vaccines with improved efficacy against tuberculosis
-
批准号:nhmrc : 302112
-
项目类别:NHMRC Project Grants
-
资助金额:$32.06万
-
财政年份:2004
-
负责人:A/Pr James Triccas
-
依托单位:
Attenuated and recombinant mycobacterial strains as novel vaccines to control tuberculosis
-
批准号:nhmrc : 226920
-
项目类别:NHMRC Project Grants
-
资助金额:$24.7万
-
财政年份:2003
-
负责人:A/Pr James Triccas
-
依托单位:
identification of genes expressed by mycobacterium tuberculosis to enhance intracellular survival
-
批准号:nhmrc : 997142
-
项目类别:Early Career Fellowships
-
资助金额:$12.99万
-
财政年份:1999
-
负责人:A/Pr James Triccas
-
依托单位:
国内基金
海外基金
中国棉铃虫核多角体病毒基因组库和分子进化
-
批准号:30540076
-
项目类别:专项基金项目
-
资助金额:8.0万元
-
批准年份:2005
-
负责人:王汉中
-
依托单位:
细菌脂蛋白(BLP)诱导LPS交叉耐受的分子机理研究
-
批准号:30471791
-
项目类别:面上项目
-
资助金额:20.0万元
-
批准年份:2004
-
负责人:肖南
-
依托单位: