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Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis

Chronic bacterial infection and the generation of T cell memory: implication for vaccination against tuberculosis
慢性细菌感染和 T 细胞记忆的产生:结核病疫苗接种的意义
批准号:
nhmrc : 570768
负责人:
A/Pr James Triccas
金额:
$36.54万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31

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中文摘要
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英文摘要
Two million people die from tuberculosis (TB) each year. The immune system is unable to eradicate the TB bacterium, and the type of immune response needed to protect against the disease is poorly understood. We will use animal models of TB infection and sophisticated immunological techniques to decipher how the TB bacterium interacts with the immune sytem and causes disease. We will also develop new TB vaccines that aim to boost the immune response in the lung, the main site of TB infection.
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Multistage vaccines for the prevention of tuberculosis
  • 批准号:
    nhmrc : 1102597
  • 项目类别:
    Project Grants
  • 资助金额:
    $60.84万
  • 财政年份:
    2016
  • 负责人:
    A/Pr James Triccas
  • 依托单位:
A new class of inhibitors for the treatment of tuberculosis
  • 批准号:
    nhmrc : 1084266
  • 项目类别:
    Project Grants
  • 资助金额:
    $48.06万
  • 财政年份:
    2015
  • 负责人:
    A/Pr James Triccas
  • 依托单位:
New candidate vaccines to prevent tuberculosis: preclinical assessment of efficacy, safety and mechanism of protection
  • 批准号:
    nhmrc : 1043519
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.62万
  • 财政年份:
    2013
  • 负责人:
    A/Pr James Triccas
  • 依托单位:
Genes of Mycobacterium tuberculosis essential for Latent Tuberculosis Infection
  • 批准号:
    nhmrc : 1051246
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.35万
  • 财政年份:
    2013
  • 负责人:
    A/Pr James Triccas
  • 依托单位:
国内基金
海外基金
中国棉铃虫核多角体病毒基因组库和分子进化
  • 批准号:
    30540076
  • 项目类别:
    专项基金项目
  • 资助金额:
    8.0万元
  • 批准年份:
    2005
  • 负责人:
    王汉中
  • 依托单位:
细菌脂蛋白(BLP)诱导LPS交叉耐受的分子机理研究