Engineering, Physical, Natural Sciences and Medicine Bridging Research in Antimicrobial resistance: Collaboration and Exchange (EMBRACE)

抗菌素耐药性的工程、物理、自然科学和医学桥接研究：合作与交流 (EMBRACE)

• 批准号: EP/M027007/1
• 负责人: Chris Toumazou
• 金额: $ 95.51万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FM027007%2F1
• 关键词: Engineering; Physical; Natural; Sciences; Medicine

This project consists of a two year programme which aims to bridge the gap between Engineering, Natural Sciences and Physical Sciences and AMR Research. The purpose of the programme is to try and engage these disciplines in multidisciplinary research which is important and relevant in tackling the catastrophic threat that antimicrobial resistance poses. The programme is principally designed to develop a cohort of interdisciplinary research fellows who through the programme, will develop a unique set of hybrid research skills, a positive attitude to multidisciplinary research and the ability to communicate across traditional academic boundaries. We aim that these individuals will become the potential future leaders in multidisciplinary research into AMR. Supporting this main aim, are a range of activities designed to bridge the gaps between disciplines, encourage researchers in different disciplines to engage in collaborative AMR research while also providing valuable learning experiences for the fellows. Activities include developing a virtual network for AMR research, organising conferences and seminars, a sandpit exercise and supporting pump-primed AMR projects.

该项目包括一个为期两年的项目，旨在弥合工程、自然科学和物理科学与抗菌素耐药性研究之间的差距。该规划的目的是努力使这些学科参与多学科研究，这对于应对抗菌素耐药性造成的灾难性威胁是重要和相关的。该计划主要旨在培养一批跨学科研究人员，他们将通过该计划培养一套独特的混合研究技能，对多学科研究的积极态度以及跨越传统学术界限的沟通能力。我们的目标是，这些人将成为未来AMR多学科研究的潜在领导者。支持这一主要目标的是一系列活动，旨在弥合学科之间的差距，鼓励不同学科的研究人员参与抗菌素耐药性的合作研究，同时为研究员提供宝贵的学习经验。活动包括为抗菌素耐药性研究开发一个虚拟网络、组织会议和研讨会、沙坑演习和支持泵启动的抗菌素耐药性项目。

项目成果

The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection

• DOI: 10.7554/elife.55692
• 发表时间: 2020-05-04
• 期刊: ELIFE
• 影响因子: 7.7
• 作者: Giraud-Gatineau, Alexandre;Coya, Juan Manuel;Tailleux, Ludovic
• 通讯作者: Tailleux, Ludovic

Data-Driven Web-Based Intelligent Decision Support System for Infection Management at Point-Of-Care: Case-Based Reasoning bene?ts and limitations

用于护理点感染管理的数据驱动的基于网络的智能决策支持系统：基于案例的推理的优点和局限性

• 发表时间: 2017
• 作者: Hernandez B

Towards a minimally invasive device for continuous monitoring of beta-lactam antibiotics

开发用于连续监测 β-内酰胺抗生素的微创装置

• DOI: 10.1016/j.ijid.2018.04.3666
• 发表时间: 2018
• 期刊: International Journal of Infectious Diseases
• 影响因子: 8.4
• 作者: Rawson T

Increased airway glucose increases airway bacterial load in hyperglycaemia.

• DOI: 10.1038/srep27636
• 发表时间: 2016-06-08
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Gill SK;Hui K;Farne H;Garnett JP;Baines DL;Moore LS;Holmes AH;Filloux A;Tregoning JS
• 通讯作者: Tregoning JS

Variability in detection of SARS-CoV-2-specific antibody responses following mild infection: a prospective multicentre cross-sectional study, London, United Kingdom, 17 April to 17 July 2020.

• DOI: 10.2807/1560-7917.es.2022.27.4.2002076
• 发表时间: 2022-01
• 期刊: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
• 作者: Pallett SJ;Jones R;Abdulaal A;Pallett MA;Rayment M;Patel A;Denny SJ;Mughal N;Khan M;Rosadas de Oliveira C;Pantelidis P;Randell P;Toumazou C;O'Shea MK;Tedder R;McClure MO;Davies GW;Moore LS
• 通讯作者: Moore LS