Integrated energy efficient microwave and unique fermentation processes for pilot scale production of high value chemicals from lignocellulosic waste

集成节能微波和独特的发酵工艺，用于从木质纤维素废物中试生产高价值化学品

• 批准号: EP/N013522/1
• 负责人: Christopher Chuck
• 金额: $ 407.34万
• 依托单位: University of Bath
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FN013522%2F1
• 关键词: Integrated; energy; efficient; microwave; unique

To meet key climate change targets, while providing sustainable economic growth, the UK must develop a robust bioeconomy. This requires the valorisation of UK-specific and abundant waste lignocelluosic streams. Currently, the expense and inefficiency of the multi-stage acid pre-treated depolymerisation and enzymatic process has limited the growth in this sector. Recently, we reported an innovative one-step microwave (MW) process for the depolymerisation of bio-wastes. This key enabling technology achieves high sugar yields despite low energy inputs. While the inhibitors formed in the process limit the growth of most yeasts, the robust yeast Metschnikowia pulcherrima (Mp) thrives on this feedstock to produce valuable 2-phenylethanol, arabinitol and lipids. This project aims to develop a pilot scale multi-product biorefinery by coupling these breakthroughs in low energy biomass treatment and unique fermentation to produce marketable compounds.

为了实现关键的气候变化目标，同时提供可持续的经济增长，英国必须发展强大的生物经济。这就需要对英国特有的大量废弃木质纤维素流进行增值。目前，多阶段酸预处理解聚和酶法的成本和效率低下限制了该领域的发展。最近，我们报告了一种用于生物废物解聚的创新一步微波（MW）工艺。尽管能源投入较低，但这项关键技术仍实现了高糖产量。虽然在该过程中形成的抑制剂限制了大多数酵母的生长，但健壮的酵母Metschnikowia pulcherrima（Mp）在这种原料上茁壮成长，产生有价值的2-苯基乙醇、阿拉伯糖醇和脂质。该项目旨在开发一个中试规模的多产品生物精炼厂，通过将这些低能量生物质处理和独特的发酵技术结合起来，生产可销售的化合物。

项目成果

The history, state of the art and future prospects for oleaginous yeast research.

• DOI: 10.1186/s12934-021-01712-1
• 发表时间: 2021-12-07
• 期刊: Microbial cell factories
• 影响因子: 6.4
• 作者: Abeln F;Chuck CJ
• 通讯作者: Chuck CJ

Combining steam distillation with microwave-assisted pyrolysis to maximise direct production of levoglucosenone from agricultural wastes

• DOI: 10.1039/c8gc02994f
• 发表时间: 2019-03-21
• 期刊: GREEN CHEMISTRY
• 影响因子: 9.8
• 作者: Bouxin, Florent P.;Clark, James H.;Budarin, Vitally
• 通讯作者: Budarin, Vitally

Additional file 1 of The history, state of the art and future prospects for oleaginous yeast research

含油酵母研究的历史、现状和未来前景的附加文件 1

• DOI: 10.6084/m9.figshare.17141212
• 发表时间: 2021
• 作者: Abeln F

Lipid production through the single-step microwave hydrolysis of macroalgae using the oleaginous yeast Metschnikowia pulcherrima

• DOI: 10.1016/j.algal.2019.101411
• 发表时间: 2019-03-01
• 期刊: ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
• 影响因子: 5.1
• 作者: Abeln, Felix;Fan, Jiajun;Chuck, Christopher J.
• 通讯作者: Chuck, Christopher J.

Electrical conductivity of beech sawdust using graphite catalytic coating: unlocking the microwave-assisted thermolysis efficiency of lignocellulosic biomass.

• DOI: 10.1039/d1se00610j
• 发表时间: 2021-07-27
• 期刊: Sustainable energy & fuels
• 影响因子: 5.6
• 作者: Bouxin FP;Fan J;Budarin VL;Clark JH
• 通讯作者: Clark JH