课题基金 / 基金详情

NEW TECHNOLOGY FOR IMPROVING HIGH MASS ION DETECTION

NEW TECHNOLOGY FOR IMPROVING HIGH MASS ION DETECTION
改进高质量离子检测的新技术
批准号:
3505254
负责人:
JOHN F MAHONEY
金额:
$4.99万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-03-15 至 1989-09-14
关键词:

项目摘要

项目成果

JOHN F MAHONEY的其他基金

相似基金

相关文献

中文摘要
翻译
此应用程序的长期目标有两个:到
英文摘要
The long term objectives of this application are twofold: to provide a clear understanding of the physical mechanisms governing the increases in detection sensitivity demonstrated to date by the proposed methodology and to construct prototype hardware from which commercial high mass detection instrumentation can be designed and manufactured. The specific aim of Phase I research is to explore a promising new technology for detecting high mass ions which does not depend exclusively on kinetic ejection of secondary electrons and does not use excessively high voltages for operation. Recent approaches for improving ion detection sensitivity use post-dynode elements to achieve current amplification. This application addresses the feasibility of improving the yield of secondary negative particles at the ion impacted dynode by altering the dynode surface. By providing a dynode treated to lower the surface work function, advantageous use can be made of the physical and electronic properties inherent in the structure of large biomolecules. Enhanced yields of negative fragment ions and possibly photoemissive or thermionic electrons are expected from dynode surfaces treated with an overlayer of cesium-oxygen. The commercial application for ion detectors based on the proposed techniques would extend not only to magnetic sector and TOF instruments, but quadrupoles as well.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
RAPID, SENSITIVE SEQUENCING OF 2-D GEL SEPARATED PROTEIN
  • 批准号:
    2392219
  • 项目类别:
  • 资助金额:
    $35.25万
  • 财政年份:
    1994
  • 负责人:
    JOHN F MAHONEY
  • 依托单位:
RAPID,SENSITIVE SEQUENCING OF 2-D GEL SEPARATED PROTEINS
  • 批准号:
    2190419
  • 项目类别:
  • 资助金额:
    $7.5万
  • 财政年份:
    1994
  • 负责人:
    JOHN F MAHONEY
  • 依托单位:
RAPID, SENSITIVE SEQUENCING OF 2-D GEL SEPARATED PROTEIN
  • 批准号:
    2190420
  • 项目类别:
  • 资助金额:
    $39.75万
  • 财政年份:
    1994
  • 负责人:
    JOHN F MAHONEY
  • 依托单位:
LASER-DROPLET TOF MASS SPECTROMETRY AND DNA SEQUENCING
  • 批准号:
    2209105
  • 项目类别:
  • 资助金额:
    $20.79万
  • 财政年份:
    1993
  • 负责人:
    JOHN F MAHONEY
  • 依托单位:
海外基金