NEW, HIGH Z SEMICONDUCTOR SENSOR FOR POSITRON TOMOGRAPHY

用于正电子断层扫描的新型高阻抗半导体传感器

• 批准号: 3507943
• 负责人: MICHAEL R. SQUILLANTE
• 金额: $ 25.33万
• 依托单位: RADIATION MONITORING DEVICES, INC.
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-03-01 至 1992-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3507943
• 关键词: biomaterial development /preparation; biomaterial evaluation; biomedical equipment development; biosensor device; clinical biomedical equipment; gamma radiation; positron emission tomography; radionuclides; semiconduction; thallium

(Adapted from investigator's abstract): Positron Emission Tomography (PET) is a noninvasive medical imaging technique which provides an image of a positron emitting radio pharmaceutical and its distribution in the body on a metabolic level. It is becoming an important fundamental tool for both clinical diagnosis and medical research. The heart of this instrument is a large, circular array of gamma ray detectors. The complexity, cost and difficulty of building an instrument with hundreds of these bulky and fragile photosensors is a significant problem. The availability of a suitable solid state sensor to replace the phototubes and scintillator crystals would be a major breakthrough in the design of high resolution positron tomography cameras. Such a sensor would detect the 511 keV photons directly to produce an electronic pulse without an intermediate optical conversion. It would be a small, stable device which would make construction of rugged, compact multi-detector arrays for PET systems possible. At Radiation Monitoring Devices, Inc., gamma ray detectors made from a new semi-conductor material, thallium bromide (T1Br) have been investigated. T1Br has the same effective Z as bismuth germinate (BGO), the leading scintillator material used for PET, and higher density. Preliminary results indicate T1Br has potential for low noise and high energy resolution. The properties of this material make it a unique semiconductor which appears to have the characteristics required to finally make a semiconductor based PET camera.

（改编自研究者的摘要）：正电子发射断层扫描 (PET) 是一种非侵入性医学成像技术，可提供图像 正电子发射放射性药物及其在体内的分布 身体在新陈代谢水平上。 它正在成为重要的基础工具 用于临床诊断和医学研究。 这的心 仪器是一个大型的伽马射线探测器圆形阵列。 这 构建具有数百个仪器的复杂性、成本和难度 这些笨重且脆弱的光电传感器是一个重大问题。 可用合适的固态传感器来替代 光电管和闪烁体晶体将是该领域的重大突破 高分辨率正电子断层摄影相机的设计。 这样的传感器 将直接检测 511 keV 光子以产生电子脉冲 无需中间光学转换。 这将是一个小而稳定的 设备可以构建坚固、紧凑的多探测器 PET 系统的阵列成为可能。 在辐射监测设备公司，伽马射线探测器由一种新的 半导体材料溴化铊（T1Br）已被研究。 T1Br 与领先的萌发铋 (BGO) 具有相同的有效 Z 闪烁体所用材料为PET，且密度较高。 初步的 结果表明 T1Br 具有低噪音和高能量的潜力 解决。 这种材料的特性使其成为一种独特的 半导体似乎具有所需的特性 最终制作出基于半导体的PET相机。