LASER TREPHINATION OF THE CORNEA

这一阶段的研究结果充分证明了该方法的有效性。 实际上是对角膜进行激光环钻。现建议： 通过开发和测试完整的 激光角膜手术仪。最终的乐器将包括第二个 产生脉冲HF激光器；光学传输和对准系统； 手术台、手术显微镜和定位和定位的硬件 稳定目标角膜；微型计算机连接到激光和 提供仪器控制和监控的光学输送系统 还有手术程序。外科医生将通过以下途径操作该器械 微型计算机键盘和/或通过手或脚控制接口连接到 微型计算机。 二期工程的总体目标是完成仪器 开发，通过角膜外科研究来验证仪器的性能， 最后，使用该仪器对人体供体组织进行环钻 角膜移植。供、受者组织同时使用的集成开发环境 该仪器将在人体移植期间应用 第二阶段。

Results of this Phase I research have amply demonstrated the effectiveness and practically of laser trephination of the cornea. It is proposed to continue this project through the development and testing of a complete laser corneal surgical instrument. The final instrument will include a 2nd generation pulsed HF laser; an optical delivery and alignment system; an operating table, operating microscope, and hardware to position and stabilize the target cornea; a microcomputer interfaced to laser and optical delivery system to provide control and monitoring of the instrument and the surgical procedure. The surgeon will operate the instrument via the microcomputer keyboard, and/or via hand or foot controls interfaced to the microcomputer. The overall goal of the Phase II project is to complete instrument development, to verify instrument performance by corneal surgical studies, and finally to use the instrument for donor tissue trephination in human cornea transplantations. An IDE for both donor and recipient tissue use of the instrument in human transplantations will be applied for during the Phase II period.