LASER TREPHINATION OF THE CORNEA

第一阶段研究的结果充分证明了 实际上是角膜的激光环钻术。 提出要 通过开发和测试一个完整的 激光角膜手术仪 最后一项文书将包括第二个 第二代脉冲HF激光器;光学传递和对准系统; 手术台、手术显微镜和定位硬件， 稳定目标角膜;与激光器连接的微型计算机， 提供仪器控制和监测的光学传输系统 和外科手术 外科医生将通过以下方式操作器械： 微型计算机键盘，和/或通过手或脚控制接口， 微型计算机。 二期工程的总体目标是完成仪器 开发，通过角膜手术研究验证仪器性能， 最后将该器械用于人体供体组织环钻术 角膜移植 供者和受者组织使用的IDE 该仪器将在人类移植中应用， 第二阶段。

Results of this Phase I research have amply demonstrated the effectiveness and practically of laser trephination of the cornea. It is proposed to continue this project through the development and testing of a complete laser corneal surgical instrument. The final instrument will include a 2nd generation pulsed HF laser; an optical delivery and alignment system; an operating table, operating microscope, and hardware to position and stabilize the target cornea; a microcomputer interfaced to laser and optical delivery system to provide control and monitoring of the instrument and the surgical procedure. The surgeon will operate the instrument via the microcomputer keyboard, and/or via hand or foot controls interfaced to the microcomputer. The overall goal of the Phase II project is to complete instrument development, to verify instrument performance by corneal surgical studies, and finally to use the instrument for donor tissue trephination in human cornea transplantations. An IDE for both donor and recipient tissue use of the instrument in human transplantations will be applied for during the Phase II period.