PURCHASE OF A SCANNING MICRODENSITOMETER AND COMPUTER

购买扫描微密度计和计算机

• 批准号: 3519087
• 负责人: KENNETH ALLEN TAYLOR
• 金额: $ 4.94万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-12-01 至 1985-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3519087
• 关键词: computers; densitometry; enzyme structure; membrane structure; muscle function

The Anatomy Department of Duke University has a strong program for the study of biological structure and function with the electron microscope as a major investigative tool. The department combines excellent electron microscope facilities, expertise in freeze-fracture, ultramicrotomy, and frozen hydrated specimen techniques, a unique liquid helium cryomicroscope, and Fourier transform image analysis capability. The department's program for 3-dimensional image reconstructions through electron micrograph tilt data has been developing based upon a home built microdensitometer which is no longer capable of meeting our technical requirements. The increasing use of this densitometer by researchers outside of the department is an indication of the need for an advanced image scanning facility in the Research Triangle area. We are applying for funds to purchase a Perkin-Elmer PDS 1010M scanning microdensitometer and computer hardware to support its use as a shared facility. This instrument will overcome the deficiencies in our current system and provide enhanced capabilities for selection and display of the data.

杜克大学解剖学系有一个强大的计划， 用电子显微镜研究生物结构和功能 一个重要的调查工具 该部门结合了优秀的电子 显微镜设施，冷冻断裂，超微切片术， 冷冻水化标本技术，独特的液氦低温显微镜， 和傅里叶变换图像分析能力。 该部门的计划 对于通过电子显微照片倾斜的三维图像重建 数据是基于一个自制的显微密度计开发的， 无法满足我们的技术要求 日益 使用这种密度计的研究人员以外的部门是一个 需要先进的图像扫描设施， 三角研究区。 我们正在申请资金购买Perkin-Elmer PDS 1010 M扫描仪 显微密度计和计算机硬件，以支持其作为一个共享 设施。 该仪器将克服我们当前的缺陷 系统，并提供增强的能力，用于选择和显示 数据