Comparative analysis of human and kangaroo leishmania: defining human pathogenicity genes

利什曼病是一种全球性传染病，每年影响数百万人，造成数千人死亡。该项目将利用最近在澳大利亚发现的一种相关病原体来鉴定新的寄生虫基因和参与人类毒力的途径。比较基因组学和分子生物学的最新技术将确定导致人类疾病的基因。然后，适当的基因将用于利用澳大利亚寄生虫开发一种新的疫苗。

Leishmaniasis is a global infectious disease affecting millions and killing thousands each year. This project will utilise the recent discovery in Australia of a related pathogen to identify novel parasite genes and pathways involved in virulence in humans. The latest techniques in comparative genomics and molecular biology will identify the genes that cause human disease . Appropriate genes will then be used to develope a novel vaccine using the Australian parasite.