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ESTABLISHMENT OF A BREEDING AND RESEARCH PROGRAM

ESTABLISHMENT OF A BREEDING AND RESEARCH PROGRAM
建立育种和研究计划
批准号:
3560679
负责人:
PATRICE A FROST
金额:
$91.42万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1986
资助国家:
美国
项目状态:
已结题
起止时间:
1986-09-30 至 1995-09-29

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中文摘要
翻译
这项研究的目标是安置和管理一个117个繁殖群体 将作为国家动物资源的黑猩猩 生物医学和行为研究。具体目标是:目标1.至 维持由经过验证的繁殖者和潜在的黑猩猩组成的黑猩猩群体 繁殖者为殖民地的永久存在而努力。目标2.继续使用 后宫繁育系统,每年将提供约25个怀孕。 目标3.保持研究资源作为稳定的、自我延续的 通过提供优质的畜牧业、兽医护理和新的 住房设施。目标4.开发一台准确而全面的计算机 该系统将提供高质量的动物健康长期记录, 血统、行为和研究用途。目标5.创建一种新的行为 生物学部门,将发展应用和基础的行为研究 支持黑猩猩长期研究目标的计划 育种和研究计划。 这个拟议的殖民地有77名已确认的饲养员和40名潜在的饲养员。 将使用后宫系统(1雄+3雌)来提供 遗传多样性,防止广泛的疾病传播,以及 极好的复制品。大约50%产生的黑猩猩将 每年都会被保留下来,作为最终的替代繁殖者。该比率 将是四个雌性对一个雄性。注定要繁殖的婴儿将是 和他们的母亲一起离开了一年。断奶后,它们将被安置在 在大型室内/室外住房的同龄人小组中。 在新的赠款期间,将建造一座新的1050万美元的建筑。整个 国家黑猩猩繁育研究计划动物将被安置在 室内/室外区域,可进入运动场。 一个计算机网络系统,使设施能够建立一个 将首次建立集中的最新数据库。 对黑猩猩群体的行为管理和研究将使PRL 为心理充实、繁衍、社会性行为提供项目 需要康复的动物的发育和行为改变 在他们返回PRL后在生物医学研究中使用。最初, 对黑猩猩行为的研究将是非常重要的 集团/后宫分配到新设施。
英文摘要
The objective of the study is to house and manage a breeding colony of 117 chimpanzees that will serve as a national resource of animals for biomedical and behavioral research. The specific aims are: Aim 1. To maintain a colony of chimpanzees composed of proven breeders and potential breeders for perpetuation of the colony. Aim 2. To continue the use of the harem breeding system which will provide about 25 pregnancies per year. Aim 3. To maintain the research resource as a stable, self-perpetuating colony by providing excellent animal husbandry, veterinary care, and a new housing facility. Aim 4. To develop an accurate and thorough computer system that will provide high quality long term records of animal health, pedigree, behavior, and research uses. Aim 5. To create a new behavioral biology division that will develop an applied and basic behavioral research program which will support the long-term research goals of the Chimpanzee Breeding and Research Program. The proposed colony has 77 confirmed breeders and 40 potential breeders. A harem system (1 male + 3 females) of breeding will be used to provide genetic diversity, protection against widespread disease transmission, and excellent reproduction. Approximately 50% of the chimpanzees produced will be retained each year to serve as eventual replacement breeders. The ratio will be four females to one male. Infants destined for breeding will be left with their mothers for one year. After weaning, they will be housed in peer groups in large indoor/outdoor housing. A new $10.5 million will be built during the new grant period. The entire National Chimpanzee Breeding Research Program animals will be housed in indoor/outdoor quarters with access to exercise yards. A computer network system that will enable the facility to establish a centralized up to date data base will established for the first time. Behavioral management and studies of the chimpanzee colony will enable PRL to provide programs for psychological enrichment, breeding, sociosexual development, and modifying behaviors of animals in need of rehabilitation following use in biomedical research after their return to PRL. Initially, of significant importance will be the studying of chimpanzees' behavior for group/harem allocation into the new facility.
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THERAPIES FOR PROGESTIN CONTRACEPTIVE INDUCED BLEEDING
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