An Aberration Corrected STEM with Integrated Science Driven AI to Quantify Dynamic Functionality in Advanced Energy Technologies and Biomaterials

利用综合科学驱动的 AI 进行像差校正 STEM，以量化先进能源技术和生物材料的动态功能

• 批准号: EP/V05385X/1
• 负责人: Nigel Browning
• 金额: $ 617.73万
• 依托单位: University of Liverpool
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FV05385X%2F1
• 关键词: Aberration; Corrected; STEM; Integrated; Science

We will install a 300kV aberration corrected STEM that utilises artificial intelligence (AI) to simultaneously improve the temporal resolution and precision/sensitivity of images while minimizing the deleterious effect of electron beam damage. Uniquely, this microscope goes beyond post-acquisition uses of AI, and integrates transformational advances in data analytics directly into its operating procedures - experiments will be designed by and for AI, rather than by and for a human operator's limited visual acuity and response time. This distributed algorithm approach to experimental design, is accomplished through a compressed sensing (CS) framework that allows measurements to be obtained under extremely low dose and/or dose rate conditions with vastly accelerated frame rates. Optimizing dose / speed / resolution permits diffusion to be imaged on the atomic scale, creating wide-ranging new opportunities to characterise metastable and kinetically controlled materials and processes at the forefront of innovations in energy storage and conversion, and the wide range of novel engineering/medical functionalities created by nanostructures, composites and hybrid materials. The microscope incorporates in-situ gas / liquid / heating / cryo and straining / indentation stages to study the dynamics of synthesis, function, degradation / corrosion and regeneration / recycling on their fundamental length and time scales. It will be housed in the Albert Crewe Centre (ACC), which is a University of Liverpool (UoL) shared research facility (SRF) specialising in new experimental strategies for high-resolution/operando electron microscopy in support of a wide range of academic/industrial user projects. UoL supports all operational costs for the SRFs (service contracts, staff, consumables, etc), meaning that access to the microscope will always be "free at the point of use" for all academic users. This open accessibility is managed through a user-friendly online proposal submission and independent peer review mechanism linked to an adaptable training/booking system, which allows the ACC to provide extensive research opportunities and training activities for all users. In particular, for early career scientists, we commit experimental resources supporting UoL's commitment to the Prosper project for flexible career development and the Research Inclusivity in a Sustainable Environment (RISE) initiative that is creating a research culture maximising inclusivity and diversity synergistically with encouraging creativity and innovation. This new microscope aligns to several priority areas of research into materials, energy and personalised medicine at the UoL, priority research areas of EPSRC and national facilities in electron microscopy, imaging and materials science, and UKRI plans for infrastructure growth (https://www.ukri.org/research/infrastructure/). In addition to supporting extensive research programs at UoL linked to investments in the Materials Innovation factory (MIF), the Stephenson Institute for Renewable Energy (SIRE) and the new Digital Innovation Facility (DIF), this unique and complimentary microscope will be affiliated to and leverage from partnership with the national microscopy facilities at Harwell (ePSIC) and Daresbury (UKSuperSTEM) and the Henry Royce Institute, as well as form extensive research links to the Rosalind Franklin Institute and the Faraday Institution. We have established (and will expand through outreach activities) an extensive network of partners/collaborators from the N8 university group, Johnson Matthey and NSG, the Universities of Swansea, Birmingham, Warwick, Oxford, Cambridge, Loughborough, Edinburgh and Glasgow and Northwest UK area SME's as well as from universities in the USA, Ireland, Germany, Japan, France, Italy, Denmark, India, Singapore, China, South Africa and Spain who will create a dynamic, innovative and collaborative community driving the long-term research impact of this facility.

我们将安装一个300 kV畸变校正STEM，利用人工智能（AI）同时提高图像的时间分辨率和精度/灵敏度，同时最大限度地减少电子束损伤的有害影响。独特的是，这种显微镜超越了人工智能的收购后使用，并将数据分析的变革性进步直接集成到其操作程序中-实验将由人工智能设计，而不是由人类操作员有限的视觉敏锐度和响应时间设计。这种分布式算法方法的实验设计，是通过压缩传感（CS）框架，允许测量获得极低的剂量和/或剂量率条件下大大加快帧速率。优化剂量/速度/分辨率允许在原子尺度上对扩散进行成像，为在能量存储和转换的创新前沿的亚稳态和动力学控制的材料和工艺以及由纳米结构，复合材料和混合材料创造的广泛的新型工程/医疗功能创造了广泛的新机会。该显微镜结合了原位气体/液体/加热/低温和应变/压痕阶段，以研究其基本长度和时间尺度上的合成，功能，降解/腐蚀和再生/回收的动态。它将被安置在阿尔伯特克鲁中心（ACC），这是一个利物浦大学（UoL）的共享研究设施（SRF），专门从事高分辨率/operando电子显微镜的新实验策略，以支持广泛的学术/工业用户项目。UoL支持SRF的所有运营成本（服务合同，员工，消耗品等），这意味着所有学术用户都可以“免费使用”显微镜。通过方便用户的在线提案提交和独立的同行审查机制管理这种开放的可访问性，该机制与适应性强的培训/预订系统相联系，使行政协调会能够为所有用户提供广泛的研究机会和培训活动。特别是，对于早期的职业科学家，我们承诺实验资源支持UOL的承诺，以profitness项目灵活的职业发展和研究包容性在可持续环境（上升）倡议，这是创造一个研究文化最大化的包容性和多样性协同鼓励创造力和创新。这种新的显微镜与UoL的材料，能源和个性化医学研究的几个优先领域，EPSRC和电子显微镜，成像和材料科学国家设施的优先研究领域以及UKRI基础设施增长计划（https：//www.ukri.org/research/infrastructure/）保持一致。除了支持与材料创新工厂（MIF），斯蒂芬森可再生能源研究所（SIRE）和新的数字创新设施（DIF）投资相关的UoL广泛的研究计划外，这种独特的免费显微镜将隶属于Harwell（ePSIC）和达雷斯伯里的国家显微镜设施并与之合作（UKSuperSTEM）和亨利罗伊斯研究所，以及形成广泛的研究联系，罗莎琳德富兰克林研究所和法拉第研究所。我们建立（并将通过外联活动扩大）来自N8大学集团、约翰逊信万丰和NSG、斯旺西大学、伯明翰大学、沃里克大学、牛津大学、剑桥大学、拉夫堡大学、爱丁堡大学、格拉斯哥大学和英国西北部地区中小企业以及美国、爱尔兰、德国、日本、法国、意大利、丹麦、印度、新加坡、中国、南非和西班牙将创建一个充满活力，创新和协作的社区，推动该设施的长期研究影响。