The UK National Crystallography Service 2022-27

英国国家晶体学服务中心 2022-27

• 批准号: EP/W02098X/1
• 负责人: Simon Coles
• 金额: $ 511.05万
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW02098X%2F1
• 关键词: UK; National; Crystallography; Service; 2022

The NCS facility is amongst the most powerful and highest throughput in the world. Through this next phase it will take a significant step that will clearly make it the world-leading facility. This will be achieved by harnessing upgrades to the latest cutting-edge X-ray technologies, coupled with a range of advanced techniques that expand the scope of crystallography studies that are accessible. Core business will be the ability to handle and examine samples that a typical academic crystallography unit cannot. New provision of the advanced techniques will enable crystallisation and dynamic experiments under non-ambient conditions and will cement the NCS's globally leading position. Investment in expertise and training the next generation continues to be central to the NCS, which will provide a rapid, professional and expert service for chemical crystallography to chemistry and related areas.The Core service will provide either raw/derived data being provided for processing, or a full analysis service taking a study through to publication. The ability to handle the most demanding samples in the UoS laboratory is a key feature, providing an effective filter for a follow-on synchrotron service. The NCS has regular access to the world-leading I19 beamline at Diamond Light Source. Thus, when required, the most powerful facilities are readily available to all of UK Chemistry and related disciplines, enabling rapid progress and cutting-edge research. It will be possible to perform advanced crystallographic experiments for feasibility, pump-priming or collaborative projects e.g. variable temperature, variable pressure and controlled gas environment studies. Customers from SMEs, spin-outs and large industry alike will have access to the same advanced facilities via commercial access to the professional, timely and bespoke service. Both novice and expert users will have access to appropriate training, from work-shadowing, introductory practical work and rudimentary data analysis, through to advanced analysis and solving the most demanding structural problems. A novel PG student apprenticeship scheme will extend NCS expertise out into individual departments.The NCS is well established in the research community with a proven ability to deliver a high profile and high throughput service and leads in many aspects, both nationally and globally. The facility has an exceptional publication record and is amongst the world's most prolific contributors to the CSD. The Director has been involved with NCS operations for 30 years, with the co-director working within the field for >20 years and a highly experienced team this gives a combined NCS staff expertise well in excess of 90 years. Professionalism is a trademark of the NCS - it prides itself in exemplary and rigorous processes for sample handling and tracking, data management and publishing, a bespoke user interface and an ability to deliver to a demanding set of KPIs. The environment in which the NCS is housed is ideally suited to its function. Governance and strategic direction of the facility is performed by an independent panel with wide-ranging expertise which presides over access, ensuring that the highest profile and impact science is being supported in the best possible way.Key new features for the NCS in this next phase of operation include:Reaching out to new users and sectors, the new crystallisation service underpins industry, SMEs and spin-outs, while dynamic experiments extend capability for academia;Completing upgrades to the next generation instrumentation will catapult the capability and capacity of the NCS to a new level for a lab-based facility;Several technician and apprentice schemes will train the next generation.

NCS设施是世界上最强大和最高吞吐量的设施之一。通过下一阶段，它将迈出重要一步，显然将使其成为世界领先的设施。这将通过利用最新尖端X射线技术的升级以及一系列先进技术来实现，这些技术扩大了可访问的晶体学研究范围。核心业务将是处理和检查样品的能力，一个典型的学术结晶单位不能。新提供的先进技术将使非环境条件下的结晶和动态实验成为可能，并将巩固NCS的全球领先地位。对下一代的专业知识和培训的投资仍然是NCS的核心，它将为化学晶体学和化学及相关领域提供快速，专业和专家服务。核心服务将提供原始/衍生数据进行处理，或提供完整的分析服务，将研究结果进行出版。在UoS实验室中处理最苛刻样品的能力是一个关键功能，为后续同步加速器服务提供了有效的过滤器。NCS可以定期使用Diamond Light Source的世界领先的I19光束线。因此，在需要时，最强大的设施随时提供给所有英国化学和相关学科，使快速进步和前沿研究。它将有可能进行先进的晶体学实验的可行性，泵启动或合作项目，如可变温度，可变压力和受控气体环境研究。来自中小企业、衍生企业和大型行业的客户将通过商业渠道获得专业、及时和定制的服务，从而获得同样先进的设施。新手和专家用户都将获得适当的培训，从工作阴影，介绍性实际工作和基本数据分析，到高级分析和解决最苛刻的结构问题。新的PG学生学徒计划将把NCS的专业知识扩展到各个部门。NCS在研究界已经建立了良好的基础，并已证明有能力提供高知名度和高吞吐量的服务，并在国内和全球的许多方面处于领先地位。该设施有一个特殊的出版记录，是世界上最多产的贡献者可持续发展委员会。主任参与NCS业务已有30年，联合主任在该领域工作超过20年，团队经验丰富，这使NCS工作人员的专业知识超过90年。数据主义是NCS的标志-它以样本处理和跟踪、数据管理和发布、定制用户界面以及满足一系列苛刻KPI的能力而自豪。NCS所处的环境非常适合其功能。该设施的管理和战略方向由一个拥有广泛专业知识的独立小组负责，该小组负责管理访问，确保以最好的方式支持最高知名度和影响力的科学。NCS在下一阶段的运营中的主要新功能包括：接触新用户和部门，新的结晶服务支持行业，中小企业和衍生企业，同时动态实验扩展学术界的能力;完成对下一代仪器的升级将使NCS的能力和容量提升到一个新的水平，使其成为一个基于实验室的设施;几个技术人员和学徒计划将培训下一代。