THE CONVERSION OF PHENYLALANINE TO TYROSINE

苯丙氨酸转化为酪氨酸

• 批准号: 3759381
• 负责人: S KAUFMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3759381
• 关键词: aminoacid metabolism; carbon oxygen lyase; enzyme activity; enzyme biosynthesis; enzyme induction /repression; enzyme substrate; gene expression; human tissue; phenylalanine; phenylalanine 4 monooxygenase; phosphorylation; tyrosine

In sharp contrast to the rat liver enzyme, human liver phenylalanine hydroxylase is in an activated state and can only be modestly activated by its substrate or by phosphorylation. 4A-Carbinolamine dehydratase, a component of the phenylalanine hydroxylating system also functions as part of a system that controls the expression of hepatic genes.

与大鼠肝酶形成鲜明对比的是，人肝苯丙氨酸