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REGULATION OF BLOOD PRESSURE AND CHOLESTEROL METABOLISM BY DIETARY FATS

REGULATION OF BLOOD PRESSURE AND CHOLESTEROL METABOLISM BY DIETARY FATS
膳食脂肪对血压和胆固醇代谢的调节
批准号:
3764481
负责人:
DAVID A MCCARRON
金额:
$0.0万
依托单位国家:
美国
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财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
The objective of this proposal is to compare the effect of butterfat, safflower oil, and fish oil on BP regulation in humans. We hypothesize that fish oil will lower BP to the greatest extent, while butterfat and safflower oil will not differ from one another. Ca2+ efflux from RBC membranes is expected to be higher, and platelet [Ca2+]i is expected to be lower in cells harvested from humans during the fish oil-based diet than during either the butterfat or safflower oil phases.
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EFFECT OF HMG COA REDUCTASE INHIBITION ON BLOOD PRESSURE HOMEOSTASIS IN HUMANS
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