tricloSENSE - Fluorescent sensor for triclosan and analogous chemical pollutants in water bodies

tricloSENSE - 用于检测水体中三氯生和类似化学污染物的荧光传感器

• 批准号: EP/Z000866/1
• 负责人: Graham Turnbull
• 金额: $ 26.26万
• 依托单位: University of St Andrews
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FZ000866%2F1
• 关键词: tricloSENSE; Fluorescent; sensor; triclosan; analogous

The release of environmental pollutants into water bodies present both a threat to aquatic life and to human health. Regular and widespread water pollution monitoring is needed for the early identification of pollution events, but existing laboratory-based detection technologies do not serve this need. The tricloSENSE project will develop optical sensors for trace detection in water bodies of the endocrine disruptors including triclosan, suitable for in-situ deployment and monitoring. Triclosan has been recognized as a persistent environmental pollutant which enters the environment from its widespread use as an antiseptic, preservative and disinfectant in healthcare and consumer products. It affects the endocrine system, immune system and has acute toxic effects on aquatic life. tricloSENSE will develop the first selective thin film optical sensors for triclosan and related phenol-containing endocrine disrupting pollutants. Novel fluorescent molecules will be synthesized to interact with the target analyte and produce detectable fluorescent signals. These molecules will be incorporated into thin films hosts nano-engineered to control the photophysical interactions, and hence maximise the selective detection of target pollutants. The optimised sensors will be evaluated in real water samples using a portable optoelectronic detection system. The project thereby aims to advance chemical sensing technology to enable monitoring, control, and removal of triclosan and related pollutants from effluents before entering waterbodies or reachingthe ground water.

环境污染物释放到水体中对水生生物和人类健康都构成威胁。为了及早识别污染事件，需要定期和广泛的水污染监测，但现有的基于实验室的检测技术无法满足这一需求。 tricloSENSE项目将开发光学传感器，用于水体中内分泌干扰物（包括三氯生）的痕量检测，适合现场部署和监测。三氯生已被认为是一种持久性环境污染物，因其广泛用作医疗保健和消费品中的防腐剂、防腐剂和消毒剂而进入环境。它影响内分泌系统、免疫系统，并对水生生物产生急性毒性作用。 tricloSENSE 将开发首款用于三氯生和相关含酚内分泌干扰污染物的选择性薄膜光学传感器。将合成新型荧光分子与目标分析物相互作用并产生可检测的荧光信号。这些分子将被纳入纳米工程的薄膜主体中，以控制光物理相互作用，从而最大限度地选择性检测目标污染物。优化后的传感器将使用便携式光电检测系统在真实水样中进行评估。该项目旨在推进化学传感技术，以便在进入水体或地下水之前监测、控制和去除废水中的三氯生和相关污染物。