MECHANISMS OF GROWTH CONTROL BY STEROIDS
MECHANISMS OF GROWTH CONTROL BY STEROIDS
批准号:
3095640
负责人:
E B THOMPSON
金额:
$51.47万
依托单位国家:
美国
项目类别:
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-03-04 至 1994-02-28
中文摘要
点击翻译按钮获取中文摘要
英文摘要
This proposed program project focuses upon regulation of cell proliferation
by steroid hormones. Three projects are proposed that deal with different
aspects of the manner in which glucocorticoids, estrogens, and sterols
regulate proliferation. Although the projects deal almost entirely with
malignant cells, the phenomena to be investigated have direct relevance to
regulatory processes that are common to growth control in both transformed
and normal cells. The central hypothesis to be explored proposes that
these compounds play a critical role in the neoplastic transformation and
maintenance of the proliferative state. The individual projects address
regulation of human lymphoid cells by oxysterols and glucocorticoids
(Projects I and II) and mechanisms of estrogen induction of renal tumors in
hamster kidneys (Project III).
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
Elevation of protooncogene messenger RNAs in estrogen-induced kidney tumors in the hamster.
雌激素诱导的仓鼠肾肿瘤中原癌基因信使 RNA 的升高。
DOI:
10.1093/carcin/13.4.601
发表时间:
1992
期刊:
Carcinogenesis
影响因子:
4.7
作者:
[Liehr,JG, Chiappetta,C, Roy,D, Stancel,GM]
通讯作者:
Stancel,GM
Oxysterol-induced cell death in human leukemic T-cells correlates with oxysterol binding protein occupancy and is independent of glucocorticoid-induced apoptosis.
人类白血病 T 细胞中氧甾醇诱导的细胞死亡与氧甾醇结合蛋白的占据相关,并且与糖皮质激素诱导的细胞凋亡无关。
DOI:
10.1016/0960-0760(93)90096-f
发表时间:
1993
期刊:
The Journal of steroid biochemistry and molecular biology
影响因子:
--
作者:
[Bakos,JT, Johnson,BH, Thompson,EB]
通讯作者:
Thompson,EB
Oxysterol sensitive and resistant lymphoid cells: correlation with regulation of cellular nucleic acid binding protein mRNA.
氧甾醇敏感和耐药淋巴细胞:与细胞核酸结合蛋白 mRNA 调节的相关性。
DOI:
10.1016/0960-0760(94)90070-1
发表时间:
1994
期刊:
The Journal of steroid biochemistry and molecular biology
影响因子:
--
作者:
[Ayala-Torres,S, Johnson,BH, Thompson,EB]
通讯作者:
Thompson,EB
Multidisciplinary Training in Cancer Research
-
批准号:7254240
-
项目类别:
-
资助金额:$20.83万
-
财政年份:2006
-
负责人:E B THOMPSON
-
依托单位:
Multidisciplinary Training in Cancer Research
-
批准号:7455214
-
项目类别:
-
资助金额:$21.28万
-
财政年份:2006
-
负责人:E B THOMPSON
-
依托单位:
Multidisciplinary Training in Cancer Research
-
批准号:7123169
-
项目类别:
-
资助金额:$20.86万
-
财政年份:2006
-
负责人:E B THOMPSON
-
依托单位:
FASEB Summer Conference on the Dynamic Structure of the Nuclear Hormone Receptors
-
批准号:7161308
-
项目类别:
-
资助金额:$1.0万
-
财政年份:2006
-
负责人:E B THOMPSON
-
依托单位:
STRUCTURE/FUNCTION STUDIES OF GLUCOCORTICOID RECEPTOR
-
批准号:6233601
-
项目类别:
-
资助金额:$24.59万
-
财政年份:2001
-
负责人:E B THOMPSON
-
依托单位:
STRUCTURE/FUNCTION STUDIES OF GLUCOCORTICOID RECEPTOR
-
批准号:6498203
-
项目类别:
-
资助金额:$24.59万
-
财政年份:2001
-
负责人:E B THOMPSON
-
依托单位:
CORTIVAZOL--PHASE I TRIAL IN PATIENTS WITH INCURABLE MALIGNANCIES
-
批准号:6246340
-
项目类别:
-
资助金额:$2.71万
-
财政年份:1997
-
负责人:E B THOMPSON
-
依托单位:
MECHANISMS OF GROWTH CONTROL BY STEROIDS
-
批准号:3095637
-
项目类别:
-
资助金额:$41.23万
-
财政年份:1991
-
负责人:E B THOMPSON
-
依托单位:
MECHANISMS OF GROWTH CONTROL BY STEROIDS
-
批准号:3095639
-
项目类别:
-
资助金额:$49.07万
-
财政年份:1991
-
负责人:E B THOMPSON
-
依托单位:
STEROID HORMONES, HIV-INFECTED CELLS AND HIV GENES
-
批准号:3241645
-
项目类别:
-
资助金额:$15.22万
-
财政年份:1989
-
负责人:E B THOMPSON
-
依托单位:
STEROID HORMONES, HIV-INFECTED CELLS AND HIV GENES
-
批准号:3241641
-
项目类别:
-
资助金额:$15.11万
-
财政年份:1989
-
负责人:E B THOMPSON
-
依托单位:
STEROID HORMONES, HIV-INFECTED CELLS AND HIV GENES
-
批准号:3241643
-
项目类别:
-
资助金额:$13.97万
-
财政年份:1989
-
负责人:E B THOMPSON
-
依托单位:
STEROID HORMONES, HIV-INFECTED CELLS AND HIV GENES
-
批准号:3241644
-
项目类别:
-
资助金额:$14.24万
-
财政年份:1989
-
负责人:E B THOMPSON
-
依托单位:
OXYSTEROL BINDING PROTEIN AND CHOLESTEROL METABOLISM
-
批准号:3236550
-
项目类别:
-
资助金额:$12.32万
-
财政年份:1986
-
负责人:E B THOMPSON
-
依托单位:
OXYSTEROL BINDING PROTEIN AND CHOLESTEROL METABOLISM
-
批准号:3236549
-
项目类别:
-
资助金额:$11.77万
-
财政年份:1986
-
负责人:E B THOMPSON
-
依托单位:
OXYSTEROL BINDING PROTEIN AND CHOLESTEROL METABOLISM
-
批准号:3236547
-
项目类别:
-
资助金额:$10.88万
-
财政年份:1986
-
负责人:E B THOMPSON
-
依托单位:
THE HUMAN GLUCOCORTICOID RECEPTORS, ITS GENE AND ACTIONS
-
批准号:3181852
-
项目类别:
-
资助金额:$27.31万
-
财政年份:1985
-
负责人:E B THOMPSON
-
依托单位:
The human glucocorticid receptor, its gene and actions
-
批准号:7015008
-
项目类别:
-
资助金额:$31.98万
-
财政年份:1985
-
负责人:E B THOMPSON
-
依托单位:
THE HUMAN GLUCOCORTICOID RECEPTOR, ITS GENE AND ACTIONS
-
批准号:3181858
-
项目类别:
-
资助金额:$29.05万
-
财政年份:1985
-
负责人:E B THOMPSON
-
依托单位:
HUMAN GLUCOCORTICOID RECEPTOR, ITS GENE AND ACTIONS
-
批准号:2090440
-
项目类别:
-
资助金额:$2.03万
-
财政年份:1985
-
负责人:E B THOMPSON
-
依托单位:
海外基金