Culture-independent microbiology: reducing delays in the diagnosis of severe infections and detection of antimicrobial resistance from days to hours.

独立于培养的微生物学：将严重感染诊断和抗菌药物耐药性检测的延迟从数天缩短至数小时。

• 批准号: nhmrc : 2004298
• 金额: $ 94.96万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/culture-independent-microbiology-days-hours/1780314
• 关键词: Culture; independent; microbiology; reducing; delays

Serious infections require early effective antibiotic treatment. To provide evidence that an antibiotic will be effective, current tests take 2-5 days and this leads to a reliance on broad spectrum antibiotics, which can cause harm. Our new diagnostic methods, can produce results in 4-6 hours. We will demonstrate the real-world benefit of these methods by assessing samples taken from patients with three high risk infections and compare our test to currently available results.

严重的感染需要早期有效的抗生素治疗。为了提供抗生素有效的证据，目前的测试需要2-5天，这导致对广谱抗生素的依赖，这可能会造成伤害。我们的新诊断方法，可以在4-6小时内产生结果。我们将通过评估从患有三种高风险感染的患者中采集的样本，并将我们的测试与目前可用的结果进行比较，来证明这些方法的实际益处。