CORE CLINICAL NUTRITION RESEARCH CENTER

UAB临床营养研究组的主要目的是 在临床中产生、促进和加强跨学科研究 强调预防疾病的基础营养。主要是癌症， 以及改善病人护理。UAB-CNRU致力于 完善营养教育，从传播上发声 向公众提供营养信息，进行健康教育 营养科学方面的专业人员和研究人员。要完成 这些目标CNRU支持一个关键人员的管理核心 负责规划、评估和管理方案和财政 广泛的研究和培训活动的事务。这个 以中七核心形式提供共享资源 实验室/设施和为青年提供的启动资助 研究人员是用于促进营养的主要机制 研究。强大的营养教育成分和营养 信息服务是实现我们的教育的核心 目标包括研究开发、评估 教育方法论。 中国人民大学研究基地扩大了十多倍。超过40岁 项目(28个是现行赠款/合同，17个是 营养和癌症受益于CNRU通过访问Core提供的支持 服务，或通过作为中国北车试点项目提供资金。CNRU合作 与UAB和临床学院的综合癌症中心合作 以及全校的基础科学系。十大协作项目 与其他大学或研究所合作，包括三所CNRU (加州大学洛杉矶分校、加州大学戴维斯分校和范德比尔特大学)和一所海外大学 正在取得的最新科学成就包括：展示 宫颈和支气管癌前病变的改善 补充叶酸和B12的上皮细胞；完全预防 雌激素/孕酮联合治疗大鼠实验性乳腺癌 治疗；新的潜在化学预防药物的合成和评价 维甲酸；发现一种新的骨细胞附着蛋白，可能在 在癌症促进中的作用；演示了启动-促进 乙醇诱发实验性乳腺癌：一种新型化合物的合成 抗恶心药物研究新方法的发展 身体成分，以及更多。对我们核心设施的主要补充 包括用于癌症研究的动物设施，以及计算机图像 分析实验室即将投入使用。

The primary purpose of the Clinical Nutrition Research Unit at UAB is to generate, promote and strengthen interdisciplinary reseach in clinical and basic nutrition emphasizing prevention of disease. primarily cancer, and the improvement of patient care. The UAB-CNRU is committed to the improvement of nutrition education, from the dissemination of sound nutrition information to the public, to the education of health professionals and investigators in nutrition sciences. To accomplish these goals the CNRU supports an Administrative Core of Key personnel responsible for planning evaluating and managing programmatic and fiscal affairs of a broad spectrum of research and training activities. The provision of shared resources in the form seven Core laboratories/facilities and the support of starter grants for young investigators are the main mechanisms used for promotion of nutrition research. A strong Nutrition Education component and a Nutrition Information Service are central to the attainment of our educational objectives including research on the development, an evaluation of educational methodologies. The CNRU Research Base has expanded more than ten times. Over forty project (twenty-eight are active grants/contracts, and seventeen are in nutrition and cancer benefit from CNRU support via access to Core services, or through funding as CNR pilot projects. The CNRU collaborates with the Comprehensive Cancer Center at UAB an with faculty from clinical and basic sciences Departments campus-wide. Ten collaborative projects with other Universities or Research Institutes, including three CNRU' (UCLA, UC-Davis and Vanderbilt University) and a university abroad, are in progress Recent scientific accomplishments include: Demonstration of improvement in pre-neoplastic lesions of the cervix and the bronchial epithelium by folate and B12 supplementation; complete prevention of experimental mammary cancer in rats by combination estrogen/progesterone treatment; synthesis and evaluation of new potential chemo-preventive retinoids; discovery of a new bone cell-attachment protein possibly in volved in cancer promotion; demonstration of initiation-facilitation of experimental mammary carcinogenesis by ethanol; synthesis of a new type of antisickling compounds development of new methods for the study of body composition, and more. Major additions to our Core facilities include animal facilities for cancer research, and a computerized Image Analysis laboratory soon to become operational.