STUDIES ON THE REGULATION OF PLATELET ACTIVATION

血小板活化调控的研究

• 批准号: 3874359
• 负责人: R I PARKER
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3874359
• 关键词: acid base balance; calcium flux; granule; human tissue; ion transport; peptides; phosphorylation; platelet activation; platelet aggregation

These studies are directed to better understanding the various pathways that regulate the activation of platelets. Platelets will be activated under controlled conditions and various endpoints of platelet activation will be monitored. These endpoints will include, but are not limited to aggregation, shape change, granule secretion-, Ca+2 flux, ion transport, cytoplasmic pH, and peptide phosphorylation.

这些研究旨在更好地了解各种途径 调节血小板的活化将激活血小板 在受控条件和血小板活化的各种终点下 将受到监控。这些终点包括但不限于 聚集、形状变化、颗粒分泌、Ca+2通量、离子转运、 细胞质pH和肽磷酸化。