ABNORMAL CLOTTING STUDIES IN HODGKIN'S DISEASE

霍奇金病的凝血异常研究

• 批准号: 4692041
• 负责人: R I PARKER
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4692041
• 关键词: Hodgkin's disease; blood coagulation disorders; clotting factor; fibrinogen; hemostasis; human tissue; lymphoma; thrombin

Patients with Hodgkin's disease in this institution have often presented with abnormal clotting studies, particularly thrombin time. Because of liver involvement with lymphoma abnormal fibrinogen species have been searched for. In addition, because a retrospective analysis of all patients with Hodgkin's disease at this institution between 1/74 and 3/83 revealed a 33% incidence of abnormal coagulation studies, this study has been expanded to look at other clotting abnormalities in addition to fibrinogen.

该机构的霍奇金病患者经常出现 凝血研究异常，尤其是凝血酶时间。 由于 肝脏受累淋巴瘤异常纤维蛋白原种类已被证实 搜索过。 另外，由于所有的回顾性分析 该机构患有霍奇金病的患者比例在 1/74 至 3/83 之间 一项研究显示，凝血异常的发生率为 33%，该研究 已扩展到除以下情况之外的其他凝血异常 纤维蛋白原。