HOST RESPONSE IN PERIODONTAL DISEASE

牙周疾病的宿主反应

• 批准号: 3963863
• 负责人: ROBERT J. GENCO
• 金额: --
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3963863
• 关键词: Actinomyces; antibacterial antibody; bactericidal immunity; complement; dental plaque; gingivitis; human subject; human tissue; immunity; leukocyte activation /transformation; microorganism immunology; neutrophil; oral bacteria; periodontitis; periodontium disorder

Several specific approaches are defined to elucidate participation of the host's immunologic responses to oral microbial products in human periodontal diseases. A. To determine the relationship of serum and local antibodies to the oral microbiota in various periodontal patients. B. To measure phagocyte function in periodontal diseases. C. To assess lymphocyte function in periodontal diseases, with an emphasis on control mechanisms and mechanisms of immunopathology.

定义了几个具体的方法来阐明参与