HOST RESPONSE IN PERIODONTAL DISEASE

牙周疾病的宿主反应

• 批准号: 4692785
• 负责人: ROBERT J. GENCO
• 金额: --
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4692785
• 关键词: Actinomyces; antibacterial antibody; bactericidal immunity; complement; dental plaque; gingivitis; human subject; human tissue; immunity; leukocyte activation /transformation; microorganism immunology; neutrophil; oral bacteria; periodontitis; periodontium disorder

Several specific approaches are defined to elucidate participation of the host's immunologic responses to oral microbial products in human periodontal diseases. A. To determine the relationship of serum and local antibodies to the oral microbiota in various periodontal patients. B. To measure phagocyte function in periodontal diseases. C. To assess lymphocyte function in periodontal diseases, with an emphasis on control mechanisms and mechanisms of immunopathology.

定义了几种具体的方法，以阐明 人体对口服微生物制品免疫应答 牙周病 A.确定血清与局部 牙周病患者的口腔微生物抗体。 B。到 测量牙周病中的吞噬细胞功能。 C.评估 牙周病中的淋巴细胞功能，重点是控制 机制和免疫病理学机制。