MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE

与特异性粘附相关的微生物抗原

基本信息

项目摘要

Seventy-one strains of viridans streptococci, classified as Streptococcus sanguis, S. gordonii, S. oralis, S. mitis or S. anginosus, by a revised taxonomic scheme, were characterized and compared by their specific adherence related properties. Significant differences were noted between species. Strains of S. sanguis, S. gordonii and S. oralis commonly expressed neuraminidase sensitive hemagglutinating activities while aggregation of acidic proline rich protein coated latex beads was noted primarily with strains of the latter two species. More strains of S. sanguis, S. gordonii and S. oralis were specifically adherent to saliva-coated hydroxyapatite than were strains of S. mitis and S. anginosus. Lactose resistant coaggregations with actinomyces were noted most frequently with S. gordonii and S. anginosus, species not involved in the primary colonization of teeth. In contrast, lactose sensitive coaggregations with actinomyces were observed with all strains of S. oralis and less frequently with the other streptococcal species. Many of these streptococci also participated in GalNAc sensitive coaagregations with certain S. sanguis and S. gordonii strains. Actinomyces with Gal and GalNAc sensitive lectins and streptococci with GalNAc sensitive lectins both coaggregated with S. oralis 34 but these bacteria did not coaggregate with a spontaneous mutant of strain 34 that lacked a cell wall polysaccharide previously shown to contain GalNAcbeta13Ga1alpha receptor regions. Other strains known to possess cell wall polysaccharides containing this disaccharide also coaggregated with streptococci expressing GalNAc sensitive lectins. Unlike actinomyces lectins, the streptococcal lectins failed to recognize Galbeta13GalNAcalpha in polysaccharide receptors of other streptococci. The association of certain adherence properties with different taxonomic groups of viridans streptococci and definition of the specificities of some of these interactions provide a basis for further ecological characterization of these oral bacteria.
71株草绿色链球菌,分类为 血链球菌(Streptococcus sanguis)、血链球菌(S. gordonii,S. oralis,S. mitis或S.心绞痛, 通过一个修订的分类方案,其特征在于,并比较其 具体的粘附相关属性。 显著差异 在物种之间。 链球菌菌株sanguis,S. gordonii和S.口腔链球菌 通常表达的神经氨酸酶敏感血凝活性 而富含酸性脯氨酸的蛋白质包被的胶乳珠粒的聚集 主要以后两个物种的菌株而闻名。 多种毒株 S. sanguis,S. gordonii和S.口腔特异性粘附于 唾液包被的羟基磷灰石比S. mitis和S. 心绞痛 乳糖抗性与放线菌的共聚集 最常见的是S。gordonii和S.心绞痛,不涉及的种属 在牙齿的最初殖民中。 相反,乳糖敏感 与放线菌的共聚集现象在所有菌株中均观察到。 口腔链球菌和较少频率与其他链球菌物种。 许多 这些链球菌也参与了GalNAc敏感性 与某些S. sanguis和S.戈登氏菌株。 具有Gal和GalNAc敏感凝集素的放线菌和具有Gal和GalNAc敏感凝集素的链球菌 GalNAc敏感凝集素均与S.第34章但是这些 细菌不与菌株34的自发突变体共聚集, 缺乏细胞壁多糖, GalNAc β 13Ga1 α受体区。 其他已知具有 含有该二糖的细胞壁多糖也共聚集 表达GalNAc敏感凝集素的链球菌。 不像 放线菌凝集素,链球菌凝集素未能识别 其他链球菌多糖受体中的Galbeta13GalNAcalpha。 某些粘附特性与不同分类学的关联 草绿色链球菌群及其特异性的定义 其中一些相互作用为进一步的生态学研究提供了基础。 这些口腔细菌的特征。

项目成果

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J O CISAR其他文献

J O CISAR的其他文献

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{{ truncateString('J O CISAR', 18)}}的其他基金

MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3939937
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3917099
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MOLECULAR BIOLOGY OF STREPTOCOCCAL RECEPTOR POLYSACCHARIDES
链球菌受体多糖的分子生物学
  • 批准号:
    2456751
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3963708
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    4692619
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3753492
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3854182
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3875195
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    5201760
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:
MICROBIAL ANTIGENS ASSOCIATED WITH SPECIFIC ADHERENCE
与特异性粘附相关的微生物抗原
  • 批准号:
    3775623
  • 财政年份:
  • 资助金额:
    --
  • 项目类别:

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宿主来源的细胞外囊泡在细菌抗原运输中刺激抗菌免疫反应的功能
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