可卡因戒断的认知神经生理学迹象-猫眼课题宝

可卡因戒断的认知神经生理学迹象

批准号：

3853851

负责人：

R I HERNING

金额：

$0.0万

依托单位：

NATIONAL INSTITUTE ON DRUG ABUSE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/3853851

关键词：

cocaine cognition disorders drug abuse therapy drug addiction drug withdrawal human subject memory disorders neural information processing neuropsychological tests questionnaires sleep disorders

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英文摘要

Cognitive impairments and sleep disruption have been reported in patients withdrawing from cocaine. The nature of these disorders have yet to be documented in clinical laboratory studies. The present study evaluates cognitive information processing in subjects on a clinical ward withdrawing from cocaine with a battery of tasks (auditory rare event monitoring, two continuous performance tasks, four Sternburg memory tests). Sleep quality and duration is monitored by a subjective questionnaire. Fourteen subjects including controls have been tested in this study over a 6 to 8 week withdrawal period. Stimulus evaluation and memory deficits were observed in the cocaine addicts. Clarification of the nature of the cognitive deficits and of sleep loss will lead to more effective treatment strategies for cocaine withdrawal.

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