EFFECTS OF ATROPINE ON COGNITIVE INFORMATION PROCESSING

一系列广泛的感觉和认知电生理任务 用于评估由以下因素造成的感觉、认知和操作缺陷 阿托品。任务包括睁眼和闭眼脑电，脑干 听觉诱发反应、图形反转视觉诱发反应 听觉罕见事件监测任务、听觉连续操作任务 Sternberg听觉记忆任务(即时任务和延迟任务)。每一个 四种剂量的阿托品(0，2，4和6毫克/70公斤)在两个 在某些场合。八名受试者已经在这些程序上进行了测试。 这项研究的目的是更好地了解 胆碱能药物对认知和表现的影响；特别是在 信息处理序列阿托品发挥作用。脑电波 而诱发反应数据已经在军事和科学上被报道 日记。阿托啡在4毫克或更大剂量时增加脑电减慢和 降低认知诱发电位和表现。脑电结果 已经发表，并在去年开始进行诱发电位分析。

An extensive battery of sensory and cognitive electrophysiological tasks is used to assess sensory, cognitive and performance deficits produced by atropine. The tasks include eyes open and eyes closed EEG, brainstem auditory evoked response, pattern reversal visual evoked response, the auditory rare event monitoring task, auditory continuous performance task and Sternberg auditory memory task (both immediate and delayed). Each of four doses of atropine (0, 2, 4 and 6 mg/70 kg) is investigated on two occasions. Eight subjects have been tested on these procedures. The purpose of the study is to better understand the effects of cholinergic agents on cognition and performance; in particular, where in the information processing sequence atropine exerts its effects. The EEG and evoked response data have been reported in military and scientific journals. Atrophine at doses 4 mg or greater increase EEG slowing and reduces cognitive evoked potentials and performance. The EEG results were published and evoked potential analysis began over the last year.